TBKBP1 and RB1CC1

Number of citations of the paper that reports this interaction (PMID 21903422)
33

Data Source:
BioGRID (affinity chromatography technology, pull down)

		TBKBP1	RB1CC1
Gene Name		TBK1 binding protein 1	RB1-inducible coiled-coil 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Cytoplasm Cytosol Nuclear Membrane Pre-autophagosomal Structure Membrane ATG1/UKL1 Signaling Complex ULK1-ATG13-FIP200 Complex
	Molecular Function	Protein Binding	Protein Binding Protein Kinase Binding
	Biological Process	Innate Immune Response	Autophagic Vacuole Assembly Liver Development Positive Regulation Of Protein Phosphorylation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Cycle JNK Cascade Heart Development Regulation Of Autophagy Positive Regulation Of Cell Size Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 21743469) Multiple sclerosis ( 22190364)
Protein-Protein Interactions		3 interactors: AGO2 APBA3 RB1CC1	9 interactors: CALCOCO2 EXOC1 GABARAP PTK2 PTK2B RFWD2 TBKBP1 UBC VHL
Entrez ID		9755	9821
HPRD ID		12239	06019
Ensembl ID		ENSG00000198933	ENSG00000023287
Uniprot IDs		A7MCY6	Q8TDY2
PDB IDs
Enriched GO Terms of Interacting Partners?		MRNA Cleavage Involved In Gene Silencing By MiRNA SiRNA Loading Onto RISC Involved In RNA Interference Negative Regulation Of Translation Involved In Gene Silencing By MiRNA Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Positive Regulation Of MRNA 3'-end Processing MiRNA Metabolic Process Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Positive Regulation Of Cell Size RNA Interference Pre-miRNA Processing Regulation Of MRNA 3'-end Processing MRNA Cleavage Negative Regulation Of Translational Initiation Positive Regulation Of MRNA Catabolic Process Production Of MiRNAs Involved In Gene Silencing By MiRNA Gene Silencing By MiRNA Cellular Response To DsRNA Posttranscriptional Gene Silencing Autophagic Vacuole Assembly Macroautophagy Gene Silencing By RNA Multicellular Organismal Development	Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Response To Stress Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Signal Complex Assembly Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Innate Immune Response Regulation Of Protein Catabolic Process Positive Regulation Of Protein Ubiquitination Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Phosphatidylinositol 3-kinase Activity Regulation Of Protein Ubiquitination Immune Response Defense Response Regulation Of Proteolysis Peptidyl-tyrosine Autophosphorylation Regulation Of Phosphatidylinositol 3-kinase Activity Response To Hypoxia Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Lipid Kinase Activity DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Negative Regulation Of Apoptotic Process Signal Transduction Involved In Cell Cycle Checkpoint Negative Regulation Of Programmed Cell Death Endothelial Cell Migration Apoptotic Process Negative Regulation Of Cell Death Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Programmed Cell Death Positive Regulation Of Cell Cycle Arrest Cell Death DNA Damage Response, Signal Transduction By P53 Class Mediator Death Response To Abiotic Stimulus Epithelial Cell Migration Positive Regulation Of Cellular Protein Metabolic Process Epithelium Migration Signal Transduction In Response To DNA Damage Immune System Process Positive Regulation Of Protein Kinase Activity Mitotic DNA Damage Checkpoint
Tagcloud ?		activator ag azacytidine azi2 cdcs clarified critical csf cycling dcs defects dendritic dispensable efficiency efficient generation gm ifn ifns immunization marrow member nap1 none production reciprocally tank tbk1 tnfr	bag3 broiler chicken chickens clusters cytoskeleton degs depth differentially discovered enrichment exact exploited fully gallus heat hsp25 hsph1 hunger id1 leg microarrays modules networks pdk qrt suffering thermoregulation yellow
Tagcloud (Difference) ?		activator ag azacytidine azi2 cdcs clarified critical csf cycling dcs defects dendritic dispensable efficiency efficient generation gm ifn ifns immunization marrow member nap1 none production reciprocally tank tbk1 tnfr	bag3 broiler chicken chickens clusters cytoskeleton degs depth differentially discovered enrichment exact exploited fully gallus heat hsp25 hsph1 hunger id1 leg microarrays modules networks pdk qrt suffering thermoregulation yellow
Tagcloud (Intersection) ?