TTI1 and TTI2

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid)

		TTI1	TTI2
Description		TELO2 interacting protein 1	TELO2 interacting protein 2
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GO Annotations	Cellular Component	Nucleus Cytoplasm TORC1 Complex TORC2 Complex TTT Hsp90 Cochaperone Complex	Nucleus TTT Hsp90 Cochaperone Complex
	Molecular Function	Protein Binding
	Biological Process	Regulation Of TOR Signaling Protein Stabilization Positive Regulation Of DNA Damage Checkpoint	Protein Stabilization Positive Regulation Of DNA Damage Checkpoint
Pathways
Drugs
Diseases
GWAS			Pulse pressure ( 30224653)
Interacting Genes		4 interacting genes: ATM RXFP4 SUMO2 TTI2	1 interacting genes: TTI1
Entrez ID		9675	80185
HPRD ID		13799	13390
Ensembl ID		ENSG00000101407	ENSG00000129696
Uniprot IDs		O43156	E5RIH5 Q6NXR4
PDB IDs		7F4U 7OLE	7OLE
Enriched GO Terms of Interacting Partners?			TORC1 Complex Positive Regulation Of DNA Damage Checkpoint TTT Hsp90 Cochaperone Complex TORC2 Complex Positive Regulation Of Cell Cycle Checkpoint Regulation Of DNA Damage Checkpoint Regulation Of TOR Signaling
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