TTI2 and TTI1

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid)

		TTI2	TTI1
Description		TELO2 interacting protein 2	TELO2 interacting protein 1
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GO Annotations	Cellular Component	Nucleus TTT Hsp90 Cochaperone Complex	Nucleus Cytoplasm TORC1 Complex TORC2 Complex TTT Hsp90 Cochaperone Complex
	Molecular Function		Protein Binding
	Biological Process	Protein Stabilization Positive Regulation Of DNA Damage Checkpoint	Regulation Of TOR Signaling Protein Stabilization Positive Regulation Of DNA Damage Checkpoint
Pathways
Drugs
Diseases
GWAS		Pulse pressure ( 30224653)
Interacting Genes		1 interacting genes: TTI1	4 interacting genes: ATM RXFP4 SUMO2 TTI2
Entrez ID		80185	9675
HPRD ID		13390	13799
Ensembl ID		ENSG00000129696	ENSG00000101407
Uniprot IDs		E5RIH5 Q6NXR4	O43156
PDB IDs		7OLE	7F4U 7OLE
Enriched GO Terms of Interacting Partners?		TORC1 Complex Positive Regulation Of DNA Damage Checkpoint TTT Hsp90 Cochaperone Complex TORC2 Complex Positive Regulation Of Cell Cycle Checkpoint Regulation Of DNA Damage Checkpoint Regulation Of TOR Signaling
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