RALGPS1 and C2orf88

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		RALGPS1	C2orf88
Gene Name		Ral GEF with PH domain and SH3 binding motif 1	chromosome 2 open reading frame 88
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Cytoplasm Plasma Membrane	Plasma Membrane
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Ral Guanyl-nucleotide Exchange Factor Activity	Protein Kinase A Regulatory Subunit Binding
	Biological Process	Small GTPase Mediated Signal Transduction Regulation Of Ral Protein Signal Transduction Positive Regulation Of Ral GTPase Activity Intracellular Signal Transduction Positive Regulation Of GTPase Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: APP C2orf88 GRB2 RALA	8 interactors: ARMC7 BATF2 MYOD1 NFKBIL1 PRKAR1A RALGPS1 TDP2 ZMIZ2
Entrez ID		9649	84281
HPRD ID		11479	14436
Ensembl ID		ENSG00000136828	ENSG00000187699
Uniprot IDs		Q5JS13	Q9BSF0
PDB IDs		3QXL
Enriched GO Terms of Interacting Partners?		Chemotaxis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Locomotion Platelet Activation Vesicle-mediated Transport Synaptic Growth At Neuromuscular Junction Neurotrophin TRK Receptor Signaling Pathway Ras Protein Signal Transduction Neurotrophin Signaling Pathway Collateral Sprouting In Absence Of Injury Membrane Raft Localization Response To External Stimulus Positive Regulation Of Cellular Component Biogenesis Collateral Sprouting Axon Midline Choice Point Recognition Exocytosis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Axon Guidance Blood Coagulation Hemostasis Response To Radiation Neuron Remodeling Branching Involved In Labyrinthine Layer Morphogenesis Secretion By Cell Axonogenesis Viral Process Axon Development Cellular Response To Growth Factor Stimulus Regulation Of Body Fluid Levels Cell Morphogenesis Involved In Neuron Differentiation Wound Healing Response To Growth Factor Small GTPase Mediated Signal Transduction Secretion Neuron Projection Morphogenesis Endocytosis Cellular Copper Ion Homeostasis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Surface Receptor Signaling Pathway Cell Activation Response To Wounding Cell Morphogenesis Involved In Differentiation Labyrinthine Layer Morphogenesis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Innate Immune Response Embryonic Placenta Morphogenesis	Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Myoblast Fate Determination Myotube Differentiation Involved In Skeletal Muscle Regeneration Skeletal Muscle Fiber Adaptation Striated Muscle Cell Development Muscle Cell Development Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Skeletal Muscle Tissue Regeneration Striated Muscle Cell Differentiation Positive Regulation Of Skeletal Muscle Fiber Development Negative Regulation Of CAMP-dependent Protein Kinase Activity Myoblast Fate Commitment Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway Skeletal Muscle Adaptation Regulation Of Transcription, DNA-templated Striated Muscle Tissue Development Muscle Cell Differentiation Regulation Of CAMP-dependent Protein Kinase Activity Muscle Tissue Development Activation Of Protein Kinase A Activity Negative Regulation Of Meiotic Nuclear Division Positive Regulation Of Ral GTPase Activity Regulation Of Ral Protein Signal Transduction Muscle Cell Fate Commitment Cardiac Muscle Cell Proliferation Regulation Of Gene Expression Positive Regulation Of Myoblast Differentiation Positive Regulation Of Myoblast Fusion Cellular Response To Estradiol Stimulus Regulation Of Skeletal Muscle Fiber Development Regulation Of Lipopolysaccharide-mediated Signaling Pathway Cellular Response To Lipid Cytoplasmic Sequestering Of Transcription Factor Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Negative Regulation Of Meiotic Cell Cycle Regulation Of Myoblast Fusion Defense Response To Protozoan Skeletal Muscle Fiber Development Cytoplasmic Sequestering Of Protein Myeloid Dendritic Cell Differentiation Negative Regulation Of Toll-like Receptor Signaling Pathway Skeletal Muscle Tissue Regeneration Response To Protozoan Myeloid Dendritic Cell Activation Regulation Of Cellular Process Growth
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