AKAP19 and NFKBIL1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		AKAP19	NFKBIL1
Description		A-kinase anchoring protein 19	NFKB inhibitor like 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Protein Kinase A Regulatory Subunit Binding	Protein Binding Transcription Regulator Inhibitor Activity
	Biological Process		Negative Regulation Of Signal Transduction Regulation Of Gene Expression Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Toll-like Receptor Signaling Pathway Negative Regulation Of Canonical NF-kappaB Signal Transduction Cellular Response To Lipopolysaccharide
Pathways
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 23128233) Early chronic obstructive pulmonary disease in never smokers ( 33235445) Eosinophil count ( 32888494) Glycated hemoglobin levels ( 34059833) Height ( 28552196) Hematocrit ( 32888494) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Monocyte percentage of white cells ( 32888494) Neonatal lupus ( 20662065) Refractive error ( 32231278) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Sepsis (90-day mortality) ( 32592749) Type 1 diabetes and autoimmune thyroid diseases ( 25936594) Type 2 diabetes ( 30054458) Ulcerative colitis ( 28067908) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		11 interacting genes: ARMC7 BATF2 CENPP FBXO7 MYOD1 NFKBIL1 PRKAR1A PRKAR2B RALGPS1 TDP2 ZMIZ2	6 interacting genes: ADIPOR1 AKAP19 CASP10 CLEC18C NME7 PEX14
Entrez ID		84281	4795
HPRD ID		14436	07043
Ensembl ID		ENSG00000187699	ENSG00000204498
Uniprot IDs		Q9BSF0	A0A0A0MRT5 A8K778 Q5STV6 Q9UBC1
PDB IDs		5HVZ
Enriched GO Terms of Interacting Partners?		CAMP-dependent Protein Kinase Complex CAMP-dependent Protein Kinase Regulator Activity CAMP-dependent Protein Kinase Inhibitor Activity Ubiquitin Protein Ligase Binding Protein Kinase A Catalytic Subunit Binding CAMP Binding Negative Regulation Of CAMP/PKA Signal Transduction Regulation Of CAMP/PKA Signal Transduction Ciliary Base Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite 5'-tyrosyl-DNA Phosphodiesterase Activity Tyrosyl-RNA Phosphodiesterase Activity Tyrosyl-DNA Phosphodiesterase Activity Myoblast Fate Determination Negative Regulation Of Intracellular Signal Transduction Response To Antipsychotic Drug Regulation Of Ral Protein Signal Transduction
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