VPS9D1 and KRT39

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		VPS9D1	KRT39
Description		VPS9 domain containing 1	keratin 39
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Endocytic Vesicle	Cytosol Cytoskeleton Intermediate Filament Keratin Filament
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding Small GTPase Binding Identical Protein Binding	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Proton Motive Force-driven ATP Synthesis Vesicle-mediated Transport	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Intermediate Filament Organization
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Mean spheric corpuscular volume ( 32888494) Platelet distribution width ( 32888494)
Interacting Genes		26 interacting genes: AAMDC AHSP AKAP9 ATOSB CCDC172 CCHCR1 DSCR9 DYDC1 HOMEZ KRT31 KRT35 KRT39 MAP1LC3A MKRN3 PNMA1 POU6F2 PSMD2 RAD51D RSPH14 SYT17 TRIM21 TRIM27 TRIM54 TTC23L UBXN11 ZNF655	34 interacting genes: ANKS1A ARMC7 BEX2 C1orf216 CCDC196 CLCNKA FAM110A GFAP HGS IGFN1 KDM1A KLHL38 KRT1 KRT2 KRT3 KRT6B KRT74 KRT76 KRT78 KRT81 KRT83 KRT85 KRT86 LMO4 PPL PRPF18 SCNM1 SHC3 SMARCE1 TGM7 TXLNB UBASH3A VPS9D1 ZNF417
Entrez ID		9605	390792
HPRD ID		08508	13750
Ensembl ID		ENSG00000075399	ENSG00000196859
Uniprot IDs		Q9Y2B5	Q6A163
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoskeleton Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Suppression Of Viral Release By Host Regulation Of Viral Transcription Negative Regulation Of Viral Transcription Radial Spoke	Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Keratinization Intermediate Filament Organization Structural Constituent Of Skin Epidermis Intermediate Filament Keratin Filament Supramolecular Fiber Organization Cytoskeleton Organization Epidermis Development Organelle Organization Structural Constituent Of Cytoskeleton Cornified Envelope Tissue Development Peptide Cross-linking
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