APOBEC3B and MIR93

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		APOBEC3B	MIR93
Description		apolipoprotein B mRNA editing enzyme catalytic subunit 3B	microRNA 93
Image			No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm Cytoplasm	Extracellular Space RISC Complex Extracellular Vesicle
	Molecular Function	RNA Binding Catalytic Activity Cytidine Deaminase Activity Protein Binding Zinc Ion Binding Hydrolase Activity Metal Ion Binding	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity
	Biological Process	Immune System Process Transposable Element Silencing Negative Regulation Of Macromolecule Biosynthetic Process Cytidine To Uridine Editing Clearance Of Foreign Intracellular DNA Innate Immune Response Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Defense Response To Virus DNA Cytosine Deamination	Negative Regulation Of Cytokine Production Negative Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of BMP Signaling Pathway Negative Regulation Of Interleukin-8 Production MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Protein Secretion Negative Regulation Of Cholesterol Efflux Negative Regulation Of Cytokine Production Involved In Inflammatory Response Negative Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Stem Cell Proliferation
Pathways		mRNA Editing: C to U Conversion Formation of the Editosome
Drugs
Diseases
GWAS		Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Breast cancer ( 29059683) Response to methotrexate in juvenile idiopathic arthritis ( 24709693)
Interacting Genes		61 interacting genes: AGR2 BNIP2 MIR1-1 MIR1-2 MIR106A MIR10B MIR128-1 MIR128-2 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A2 MIR19A MIR19B1 MIR200A MIR200B MIR205 MIR20A MIR20B MIR21 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR9-1 MIR9-2 MIR9-3 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MSL2	82 interacting genes: APOBEC3B C1QBP CPSF6 CPSF7 DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 FAM98A FUS G3BP2 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT16L1 PDCD11 PGAM5 PLRG1 PTBP1 PTBP3 PUM1 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RBMS1 RBMS2 RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TRMT1L U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZNF106
Entrez ID		9582	407050
HPRD ID		06169
Ensembl ID		ENSG00000179750	ENSG00000207757
Uniprot IDs		Q9UH17
PDB IDs		2NBQ 5CQD 5CQH 5CQI 5CQK 5SXG 5SXH 5TD5 5TKM 6NFK 6NFL 6NFM 7RW6
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Extracellular Vesicle Regulation Of Gene Expression MRNA Destabilization Regulation Of Macromolecule Biosynthetic Process RNA Destabilization Negative Regulation Of Translation Positive Regulation Of MRNA Catabolic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of MRNA Metabolic Process Regulation Of Angiogenesis Negative Regulation Of Angiogenesis Negative Regulation Of Cell Migration Negative Regulation Of Vasculature Development Extracellular Space Regulation Of Vasculature Development Negative Regulation Of Cytokine Production Negative Regulation Of Cell Motility Regulation Of Metabolic Process Negative Regulation Of Locomotion Regulation Of MRNA Stability Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of RNA Stability Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Developmental Process Regulation Of Translation Negative Regulation Of Multicellular Organismal Process Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Cell Migration Regulation Of Cell Motility Regulation Of MRNA Metabolic Process Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Endothelial Cell Migration Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway	RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Splicing MRNA Processing MRNA Metabolic Process MRNA Binding Macromolecule Metabolic Process Regulation Of MRNA Metabolic Process Regulation Of RNA Splicing Nucleus MRNA Splicing, Via Spliceosome Ribonucleoprotein Complex RNA Splicing, Via Transesterification Reactions Post-transcriptional Regulation Of Gene Expression Spliceosomal Complex Aminoacyl-tRNA Synthetase Multienzyme Complex MRNA 3'-UTR Binding Nucleoplasm Catalytic Step 2 Spliceosome Negative Regulation Of MRNA Metabolic Process Regulation Of Translation Cytoplasmic Stress Granule Regulation Of MRNA Processing MiRNA Binding TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Regulation Of MRNA Splicing, Via Spliceosome TRNA Aminoacylation Negative Regulation Of RNA Catabolic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization TRNA Metabolic Process Regulation Of RNA Stability MRNA Stabilization Regulation Of Gene Expression Nucleolus Negative Regulation Of Translation Regulation Of Macromolecule Biosynthetic Process Regulation Of MRNA Stability Positive Regulation Of Cytoplasmic Translation Ligase Activity P-body CRD-mediated MRNA Stabilization Positive Regulation Of Gene Expression Negative Regulation Of Macromolecule Metabolic Process MRNA 5'-UTR Binding
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