APOBEC3B

Description		apolipoprotein B mRNA editing enzyme catalytic subunit 3B
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GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Binding Catalytic Activity Cytidine Deaminase Activity Protein Binding Zinc Ion Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Immune System Process Transposable Element Silencing Negative Regulation Of Macromolecule Biosynthetic Process Cytidine To Uridine Editing Clearance Of Foreign Intracellular DNA Innate Immune Response Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Defense Response To Virus DNA Cytosine Deamination
Pathways		mRNA Editing: C to U Conversion Formation of the Editosome
Drugs
Diseases
GWAS		Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Breast cancer ( 29059683) Response to methotrexate in juvenile idiopathic arthritis ( 24709693)
Interacting Genes		61 interacting genes: AGR2 BNIP2 MIR1-1 MIR1-2 MIR106A MIR10B MIR128-1 MIR128-2 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A2 MIR19A MIR19B1 MIR200A MIR200B MIR205 MIR20A MIR20B MIR21 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR9-1 MIR9-2 MIR9-3 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MSL2
Entrez ID		9582
HPRD ID		06169
Ensembl ID		ENSG00000179750
Uniprot IDs		Q9UH17
PDB IDs		2NBQ 5CQD 5CQH 5CQI 5CQK 5SXG 5SXH 5TD5 5TKM 6NFK 6NFL 6NFM 7RW6
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Extracellular Vesicle Regulation Of Gene Expression MRNA Destabilization Regulation Of Macromolecule Biosynthetic Process RNA Destabilization Negative Regulation Of Translation Positive Regulation Of MRNA Catabolic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of MRNA Metabolic Process Regulation Of Angiogenesis Negative Regulation Of Angiogenesis Negative Regulation Of Cell Migration Negative Regulation Of Vasculature Development Extracellular Space Regulation Of Vasculature Development Negative Regulation Of Cytokine Production Negative Regulation Of Cell Motility Regulation Of Metabolic Process Negative Regulation Of Locomotion Regulation Of MRNA Stability Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of RNA Stability Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Developmental Process Regulation Of Translation Negative Regulation Of Multicellular Organismal Process Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Cell Migration Regulation Of Cell Motility Regulation Of MRNA Metabolic Process Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Endothelial Cell Migration Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
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