TECR and HACD2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TECR	HACD2
Gene Name		trans-2,3-enoyl-CoA reductase	3-hydroxyacyl-CoA dehydratase 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Oxidoreductase Activity, Acting On The CH-CH Group Of Donors	Protein Tyrosine Phosphatase Activity Protein Binding 3-hydroxyacyl-CoA Dehydratase Activity Enzyme Binding
	Biological Process	Triglyceride Biosynthetic Process Fatty Acid Elongation Long-chain Fatty-acyl-CoA Biosynthetic Process Very Long-chain Fatty Acid Biosynthetic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Oxidation-reduction Process	Sphingolipid Biosynthetic Process Fatty Acid Elongation Very Long-chain Fatty Acid Biosynthetic Process
Pathways		Fatty Acyl-CoA Biosynthesis Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Triglyceride Biosynthesis Synthesis of very long-chain fatty acyl-CoAs
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: HACD2 NOS3 PAXIP1	2 interactors: BCAP31 TECR
Entrez ID		9524	201562
HPRD ID		17076	17930
Ensembl ID		ENSG00000099797
Uniprot IDs		Q9NZ01	Q6Y1H2
PDB IDs		2DZJ
Enriched GO Terms of Interacting Partners?		Endothelial Cell Migration Epithelial Cell Migration Epithelium Migration Positive Regulation Of Histone H3-K36 Methylation Ameboidal-type Cell Migration Smooth Muscle Hyperplasia Smooth Muscle Adaptation Regulation Of Systemic Arterial Blood Pressure By Endothelin Negative Regulation Of Muscle Hyperplasia Regulation Of The Force Of Heart Contraction By Chemical Signal Blood Vessel Morphogenesis Arginine Catabolic Process Chorion Development Regulation Of Cell Activation Very Long-chain Fatty Acid Biosynthetic Process Positive Regulation Of Guanylate Cyclase Activity Blood Vessel Development Ovulation From Ovarian Follicle Vasculature Development Fatty Acid Elongation Nitric Oxide Biosynthetic Process Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Positive Regulation Of Histone H3-K4 Methylation Nitric Oxide Mediated Signal Transduction Positive Regulation Of DNA-templated Transcription, Initiation Positive Regulation Of CGMP Biosynthetic Process Negative Regulation Of Platelet Activation Positive Regulation Of CGMP Metabolic Process Arginine Metabolic Process Positive Regulation Of MRNA Catabolic Process Ovulation Positive Regulation Of Histone Acetylation Negative Regulation Of Potassium Ion Transport Regulation Of DNA-templated Transcription, Initiation Regulation Of CGMP Biosynthetic Process Regulation Of Histone H3-K4 Methylation Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Isotype Switching Positive Regulation Of Protein Acetylation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Nitric Oxide Metabolic Process Cell Migration Reactive Nitrogen Species Metabolic Process Regulation Of The Force Of Heart Contraction Regulation Of Platelet Activation Regulation Of CGMP Metabolic Process Cardiovascular System Development Histone H3-K4 Methylation Positive Regulation Of Vasodilation	Protein Localization To Endoplasmic Reticulum Exit Site Very Long-chain Fatty Acid Biosynthetic Process Positive Regulation Of Mitochondrial Calcium Ion Concentration Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Calcium-mediated Signaling Using Intracellular Calcium Source Fatty Acid Elongation Long-chain Fatty-acyl-CoA Biosynthetic Process Mitochondrial Calcium Ion Homeostasis Fatty-acyl-CoA Biosynthetic Process Long-chain Fatty-acyl-CoA Metabolic Process Very Long-chain Fatty Acid Metabolic Process Endoplasmic Reticulum Calcium Ion Homeostasis Triglyceride Biosynthetic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Acyl-CoA Metabolic Process Execution Phase Of Apoptosis Calcium-mediated Signaling Triglyceride Metabolic Process ER To Golgi Vesicle-mediated Transport Neutral Lipid Metabolic Process
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