CD27 and CD70

Number of citations of the paper that reports this interaction (PMID 7479974)
27

Data Source:
HPRD (in vivo)

		CD27	CD70
Gene Name		CD27 molecule	CD70 molecule
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Integral Component Of Plasma Membrane External Side Of Plasma Membrane Extracellular Vesicular Exosome	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process	Protease Binding Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding Protein Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Release Of Cytoplasmic Sequestered NF-kappaB Immunoglobulin Mediated Immune Response Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Response To Ethanol Positive Regulation Of B Cell Differentiation Positive Regulation Of JNK Cascade Negative Regulation Of T Cell Apoptotic Process Extrinsic Apoptotic Signaling Pathway	Immune Response Signal Transduction Cell-cell Signaling Cell Proliferation Extrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: CD5 CD70 SIVA1 TRAF2 TRAF3 TRAF5 UHRF2	1 interactors: CD27
Entrez ID		939	970
HPRD ID		01723	18515
Ensembl ID		ENSG00000139193	ENSG00000125726
Uniprot IDs		P26842	B4DPR8 P32970 Q53XX4
PDB IDs
Enriched GO Terms of Interacting Partners?		Apoptotic Process Programmed Cell Death Cell Death Death Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Ubiquitination Protein Modification By Small Protein Conjugation Tumor Necrosis Factor-mediated Signaling Pathway Protein Autoubiquitination Apoptotic Signaling Pathway Immune System Process Negative Regulation Of NF-kappaB Transcription Factor Activity TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Cellular Response To Tumor Necrosis Factor Extrinsic Apoptotic Signaling Pathway Regulation Of Apoptotic Process Toll-like Receptor Signaling Pathway Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cell Death Response To Tumor Necrosis Factor Positive Regulation Of NF-kappaB Transcription Factor Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Signal Transduction Activation Of Innate Immune Response Cell Proliferation Signaling Cell Communication Positive Regulation Of Innate Immune Response Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of T Cell Activation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Immune System Process Activation-induced Cell Death Of T Cells Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of Cell-cell Adhesion Regulation Of Innate Immune Response Cellular Response To Stimulus Positive Regulation Of Protein Homodimerization Activity Regulation Of T Cell Activation Positive Regulation Of Cell Activation Toll Signaling Pathway Cellular Response To Nitric Oxide Regulation Of Immunoglobulin Secretion Response To Nitric Oxide Positive Regulation Of Signal Transduction	Release Of Cytoplasmic Sequestered NF-kappaB Positive Regulation Of B Cell Differentiation Positive Regulation Of NF-kappaB Import Into Nucleus Negative Regulation Of T Cell Apoptotic Process Regulation Of B Cell Differentiation Positive Regulation Of Transcription Factor Import Into Nucleus Regulation Of NF-kappaB Import Into Nucleus Regulation Of T Cell Apoptotic Process Negative Regulation Of Leukocyte Apoptotic Process I-kappaB Kinase/NF-kappaB Signaling Regulation Of Lymphocyte Apoptotic Process Positive Regulation Of B Cell Activation Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Lymphocyte Differentiation Positive Regulation Of Protein Import Into Nucleus Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Response To Ethanol Regulation Of Lymphocyte Differentiation Positive Regulation Of Intracellular Protein Transport Regulation Of JNK Cascade Regulation Of Protein Import Into Nucleus Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Immunoglobulin Mediated Immune Response B Cell Mediated Immunity Regulation Of Stress-activated MAPK Cascade Regulation Of Protein Localization To Nucleus Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Nucleocytoplasmic Transport Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Intracellular Transport Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Regulation Of Intracellular Protein Transport Negative Regulation Of Endopeptidase Activity Leukocyte Mediated Immunity Adaptive Immune Response Negative Regulation Of Peptidase Activity Positive Regulation Of Cell Activation Positive Regulation Of Protein Transport Apoptotic Signaling Pathway Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Regulation Of Endopeptidase Activity
Tagcloud ?		alignment augments belongs cd30 cd40 cd70 coimmunoprecipitation contains disulfide dramatically eeeg homodimerization intact ligation mediator monomers p50 p52 p65 phenomena piqed pxqxt signal traf1 traf2 traf3 trafs uses works	alignment augments belongs cd27 cd30 cd40 coimmunoprecipitation contains disulfide dramatically eeeg homodimerization intact ligation mediator monomers p50 p52 p65 phenomena piqed pxqxt signal traf1 traf2 traf3 trafs uses works
Tagcloud (Difference) ?
Tagcloud (Intersection) ?		alignment augments belongs cd27 cd30 cd40 cd70 coimmunoprecipitation contains disulfide dramatically eeeg homodimerization intact ligation mediator monomers p50 p52 p65 phenomena piqed pxqxt signal traf1 traf2 traf3 trafs uses works