IMP4 and MPHOSPH10

Number of citations of the paper that reports this interaction (PubMedID 35271311)
106

Data Source:
BioGRID (biochemical, pull down, affinity chromatography technology)
HPRD (in vitro)

		IMP4	MPHOSPH10
Description		IMP U3 small nucleolar ribonucleoprotein 4	M-phase phosphoprotein 10
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GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Nucleolus Preribosome Small-subunit Processome Mpp10 Complex Ribonucleoprotein Complex	Nucleus Nucleoplasm Chromosome Nucleolus Sno(s)RNA-containing Ribonucleoprotein Complex Small-subunit Processome Mpp10 Complex Ribonucleoprotein Complex
	Molecular Function	Protein Binding RRNA Binding SnoRNA Binding RRNA Primary Transcript Binding	RNA Binding Protein Binding
	Biological Process	RRNA Processing Maturation Of SSU-rRNA Ribosome Biogenesis Ribosomal Small Subunit Biogenesis	RNA Splicing, Via Transesterification Reactions RRNA Processing RNA Processing RNA Splicing Maturation Of SSU-rRNA Ribosome Biogenesis Ribosomal Small Subunit Biogenesis
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol	rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS			Coronary artery disease ( 29212778) Metabolite levels ( 23823483)
Interacting Genes		5 interacting genes: APP LTB4R2 MPHOSPH10 S100B ZBTB7B	5 interacting genes: CSNK2A1 IMP3 IMP4 PPP1CA RNF10
Entrez ID		92856	10199
HPRD ID		10002	10404
Ensembl ID		ENSG00000136718	ENSG00000124383
Uniprot IDs		E7ENR5 Q96G21	O00566
PDB IDs		7MQ8 7MQ9 7MQA	7MQ8 7MQ9 7MQA
Enriched GO Terms of Interacting Partners?		RAGE Receptor Binding Adaptive Thermogenesis Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Regulation Of Neuronal Synaptic Plasticity Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Positive Regulation Of Neuron Differentiation Growth Cone Filopodium Positive Regulation Of Synaptic Transmission Lipoprotein Particle Memory Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Developmental Cell Growth Regulation Of Nervous System Process Microglia Development Developmental Growth Involved In Morphogenesis Positive Regulation Of G Protein-coupled Receptor Internalization Mpp10 Complex Negative Regulation Of NK T Cell Activation Negative Regulation Of NK T Cell Proliferation Positive Regulation Of SREBP Signaling Pathway Negative Regulation Of CD8-positive, Alpha-beta T Cell Differentiation Leukotriene B4 Receptor Activity Leukotriene Receptor Activity Central Nervous System Development Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Protein Homodimerization Activity Astrocyte Activation Involved In Immune Response Axonogenesis Low-density Lipoprotein Particle Mediated Signaling NK T Cell Differentiation Leukotriene Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Regulation Of Spontaneous Synaptic Transmission Regulation Of Synaptic Plasticity	Preribosome Mpp10 Complex Regulation Of Apoptotic Signaling Pathway SnoRNA Binding Protein Serine/threonine Kinase Inhibitor Activity Negative Regulation Of Apoptotic Signaling Pathway Double-strand Break Repair Via Nonhomologous End Joining Hsp90 Protein Binding Regulation Of Glial Cell Proliferation Dinitrosyl-iron Complex Binding S-nitrosoglutathione Binding Nitric Oxide Storage Prenylcysteine Oxidase Activity Oxidoreductase Activity, Acting On A Sulfur Group Of Donors, Oxygen As Acceptor Prenylcysteine Catabolic Process Farnesylcysteine Lyase Activity RRNA Binding Maturation Of SSU-rRNA Regulation Of Translational Initiation Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Protein Kinase CK2 Complex RNA Metabolic Process Symbiont-mediated Disruption Of Host Cell PML Body Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle Phase Transition DNA Damage Checkpoint Signaling Forebrain Development Regulation Of Gliogenesis Regulation Of Fibroblast Proliferation Lens Fiber Cell Apoptotic Process TRAF2-GSTP1 Complex Glutathione Derivative Biosynthetic Process Cellular Response To Cell-matrix Adhesion Learned Vocalization Behavior Hard Palate Morphogenesis Mastication Vestibulocochlear Nerve Formation Positive Regulation Of Exit From Mitosis Negative Regulation Of Saliva Secretion Iron Ion Binding Protein Serine/threonine Phosphatase Activity Protein Dephosphorylation Positive Regulation Of Termination Of DNA-templated Transcription Positive Regulation Of Termination Of RNA Polymerase II Transcription RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled Prenylated Protein Catabolic Process Small-subunit Processome Ribosomal Small Subunit Biogenesis
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