MPHOSPH10

Description		M-phase phosphoprotein 10
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nucleolus Sno(s)RNA-containing Ribonucleoprotein Complex Small-subunit Processome Mpp10 Complex Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions RRNA Processing RNA Processing RNA Splicing Maturation Of SSU-rRNA Ribosome Biogenesis Ribosomal Small Subunit Biogenesis
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Metabolite levels ( 23823483)
Novel Interacting Genes		6 novel interacting genes: C2orf78 E2F1 GSTP1 NEUROG1 PCYOX1 PPEF2
Interacting Genes		5 interacting genes: CSNK2A1 IMP3 IMP4 PPP1CA RNF10
Entrez ID		10199
HPRD ID		10404
Ensembl ID		ENSG00000124383
Uniprot IDs		O00566
PDB IDs		7MQ8 7MQ9 7MQA
Enriched GO Terms of Interacting Partners?		Preribosome Mpp10 Complex Regulation Of Apoptotic Signaling Pathway SnoRNA Binding Protein Serine/threonine Kinase Inhibitor Activity Negative Regulation Of Apoptotic Signaling Pathway Double-strand Break Repair Via Nonhomologous End Joining Hsp90 Protein Binding Regulation Of Glial Cell Proliferation Dinitrosyl-iron Complex Binding S-nitrosoglutathione Binding Nitric Oxide Storage Prenylcysteine Oxidase Activity Oxidoreductase Activity, Acting On A Sulfur Group Of Donors, Oxygen As Acceptor Prenylcysteine Catabolic Process Farnesylcysteine Lyase Activity RRNA Binding Maturation Of SSU-rRNA Regulation Of Translational Initiation Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Protein Kinase CK2 Complex RNA Metabolic Process Symbiont-mediated Disruption Of Host Cell PML Body Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle Phase Transition DNA Damage Checkpoint Signaling Forebrain Development Regulation Of Gliogenesis Regulation Of Fibroblast Proliferation Lens Fiber Cell Apoptotic Process TRAF2-GSTP1 Complex Glutathione Derivative Biosynthetic Process Cellular Response To Cell-matrix Adhesion Learned Vocalization Behavior Hard Palate Morphogenesis Mastication Vestibulocochlear Nerve Formation Positive Regulation Of Exit From Mitosis Negative Regulation Of Saliva Secretion Iron Ion Binding Protein Serine/threonine Phosphatase Activity Protein Dephosphorylation Positive Regulation Of Termination Of DNA-templated Transcription Positive Regulation Of Termination Of RNA Polymerase II Transcription RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled Prenylated Protein Catabolic Process Small-subunit Processome Ribosomal Small Subunit Biogenesis
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