DLG5 and BTBD10

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DLG5	BTBD10
Gene Name		discs, large homolog 5 (Drosophila)	BTB (POZ) domain containing 10
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Cell-cell Adherens Junction	Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	Protein Binding Beta-catenin Binding Cytoskeletal Protein Binding Receptor Signaling Complex Scaffold Activity
	Biological Process	Protein Complex Assembly Signal Transduction Negative Regulation Of Cell Proliferation Single Organismal Cell-cell Adhesion Polarized Epithelial Cell Differentiation Midbrain Development Intracellular Signal Transduction Regulation Of Apoptotic Process Apical Protein Localization Zonula Adherens Assembly Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Epithelial Tube Branching Involved In Lung Morphogenesis Protein Localization To Adherens Junction Metanephric Collecting Duct Development	Positive Regulation Of Phosphorylation Type B Pancreatic Cell Proliferation Negative Regulation Of Neuron Death
Pathways
Drugs
Diseases
GWAS		Liver enzyme levels (gamma-glutamyl transferase) ( 22001757) Obesity-related traits ( 23251661)
Protein-Protein Interactions		8 interactors: ABCA1 BTBD10 CD81 CTNNB1 DLST PFN1 SORBS3 TERF1	8 interactors: ACIN1 CDC37 CUL3 DLG5 LAMA5 MAPK3 PPP1CA PPP1CC
Entrez ID		9231	84280
HPRD ID		04972	17045
Ensembl ID		ENSG00000151208	ENSG00000148925
Uniprot IDs		Q8TDM6	B7Z228 D3DQW7 Q6P5W1 Q9BSF8
PDB IDs		1UIT
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Organelle Organization Regulation Of Cytoskeleton Organization Positive Regulation Of Protein Complex Assembly Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Cellular Metabolic Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Phosphorylation Positive Regulation Of Actin Filament Bundle Assembly Regulation Of Organelle Organization Regulation Of Protein Complex Assembly Positive Regulation Of Metabolic Process Regulation Of Stress Fiber Assembly Regulation Of Chromosome Segregation Positive Regulation Of MAPK Cascade Positive Regulation Of 1-phosphatidylinositol 4-kinase Activity Response To Drug Regulation Of Phosphorylation Negative Regulation Of Mitotic Cell Cycle, Embryonic Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Schwann Cell Proliferation Cellular Response To Insulin-like Growth Factor Stimulus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Protein Polymerization Regulation Of MAPK Cascade Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Cardiac Outflow Tract Cell Proliferation Renal Inner Medulla Development Renal Outer Medulla Development Mesenchymal Cell Proliferation Involved In Lung Development L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Telomeric Loop Formation Glial Cell Fate Determination Age-dependent Telomere Shortening Oviduct Development Regulation Of Centriole-centriole Cohesion Embryonic Epithelial Tube Formation Epithelial Tube Formation Regulation Of Microtubule Cytoskeleton Organization Positive Regulation Of Determination Of Dorsal Identity Telomere Maintenance Via Telomere Shortening Lung Induction Interleukin-1 Beta Secretion Embryonic Skeletal Limb Joint Morphogenesis Canonical Wnt Signaling Pathway Involved In Regulation Of Cell Proliferation Tube Formation Cell Proliferation Morphogenesis Of Embryonic Epithelium	Triglyceride Catabolic Process Entrainment Of Circadian Clock By Photoperiod Morphogenesis Of A Polarized Epithelium Photoperiodism Entrainment Of Circadian Clock Acylglycerol Catabolic Process Branching Morphogenesis Of An Epithelial Tube Morphogenesis Of A Branching Epithelium Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Lung Development Morphogenesis Of A Branching Structure Respiratory Tube Development Respiratory System Development Adherens Junction Assembly Glycogen Metabolic Process Epithelial Tube Morphogenesis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cell Division Circadian Regulation Of Gene Expression Tube Morphogenesis Polysaccharide Metabolic Process Zonula Adherens Assembly Negative Regulation Of Apolipoprotein Binding Adherens Junction Organization Triglyceride Metabolic Process Regulation Of Circadian Rhythm Anatomical Structure Morphogenesis Morphogenesis Of An Epithelium Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Neutral Lipid Metabolic Process Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Cell Cycle Cellular Response To Growth Factor Stimulus Integrin-mediated Signaling Pathway Response To Growth Factor Regulation Of Signal Transduction Energy Reserve Metabolic Process Trophectodermal Cellular Morphogenesis Transforming Growth Factor Beta Receptor Signaling Pathway Tissue Morphogenesis Cellular Lipid Catabolic Process Multicellular Organismal Development Organ Development Protein Localization To Adherens Junction Regulation Of Golgi Inheritance Tube Development Cell Morphogenesis Involved In Differentiation Circadian Rhythm
Tagcloud ?		12b 18rap 23r atg16l1 card15 card9 ccr6 crohn dmbt1 holds homeostatic ibd5 icoslg irf5 irgm itln1 loci lrrk2 mst1 nkx2 orchestration predispose ptger4 ptpn2 ptpn22 tl1a tnfrsf6b tnfsf15 xbp1	aggregates als amyotrophic apparatus cords dismutase fragmentation g93a ga golgi horn immunoreactivity immunostained mirror morphology neuron paraffin polyclonal poz ptdp sections sod1 spinal sporadic superoxide suppresses tar tgn
Tagcloud (Difference) ?		12b 18rap 23r atg16l1 card15 card9 ccr6 crohn dmbt1 holds homeostatic ibd5 icoslg irf5 irgm itln1 loci lrrk2 mst1 nkx2 orchestration predispose ptger4 ptpn2 ptpn22 tl1a tnfrsf6b tnfsf15 xbp1	aggregates als amyotrophic apparatus cords dismutase fragmentation g93a ga golgi horn immunoreactivity immunostained mirror morphology neuron paraffin polyclonal poz ptdp sections sod1 spinal sporadic superoxide suppresses tar tgn
Tagcloud (Intersection) ?