DLG5 and BTBD10

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DLG5	BTBD10
Description		discs large MAGUK scaffold protein 5	BTB domain containing 10
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Adherens Junction Postsynaptic Density Membrane Cell Junction Ciliary Basal Body Cell Projection Synapse Anchoring Junction Glutamatergic Synapse	Fibrillar Center Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding Beta-catenin Binding Cytoskeletal Protein Binding Signaling Receptor Complex Adaptor Activity	Protein Binding
	Biological Process	Epithelial To Mesenchymal Transition Establishment Or Maintenance Of Cell Polarity Signal Transduction Negative Regulation Of Cell Population Proliferation Tissue Development Positive Regulation Of Signal Transduction Glial Cell Differentiation Maintenance Of Cell Polarity Cell Differentiation Negative Regulation Of Cell Migration Polarized Epithelial Cell Differentiation Midbrain Development Negative Regulation Of Hippo Signaling Positive Regulation Of Hippo Signaling Intracellular Signal Transduction Negative Regulation Of T Cell Proliferation Regulation Of Apoptotic Process Apical Protein Localization Zonula Adherens Assembly Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Smoothened Signaling Pathway Animal Organ Development Regulation Of Multicellular Organismal Process Positive Regulation Of Synapse Assembly Epithelial Tube Branching Involved In Lung Morphogenesis Neuroepithelial Cell Differentiation Positive Regulation Of Dendritic Spine Development Protein-containing Complex Assembly Protein Localization To Adherens Junction Metanephric Collecting Duct Development Cell-cell Adhesion Postsynapse Organization	Type B Pancreatic Cell Proliferation Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Pathways		RHOU GTPase cycle RHOV GTPase cycle RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33339817 33547301 34315874) Alanine transaminase levels ( 29403010) Aspartate aminotransferase levels ( 33547301 34315874) Gamma glutamyl transferase levels ( 29403010 33339817) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (alkaline phosphatase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 22001757 33972514) Macular thickness ( 30535121) Obesity-related traits ( 23251661) Retinal detachment or retinal break ( 31816047) Serum alkaline phosphatase levels ( 33547301)	Progression free survival in serous epithelial ovarian cancer treated with carboplatin and paclitaxel ( 28935272)
Interacting Genes		8 interacting genes: ABCA1 BTBD10 CD81 CTNNB1 DLST PFN1 SORBS3 TERF1	8 interacting genes: ACIN1 CDC37 CUL3 DLG5 LAMA5 MAPK3 PPP1CA PPP1CC
Entrez ID		9231	84280
HPRD ID		04972	17045
Ensembl ID		ENSG00000151208	ENSG00000148925
Uniprot IDs		Q8TDM6	B7Z503 D3DQW7 Q9BSF8
PDB IDs		1UIT
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Component Organization Positive Regulation Of Cellular Component Biogenesis Cellular Response To Low-density Lipoprotein Particle Stimulus Positive Regulation Of Protein-containing Complex Assembly Focal Adhesion Positive Regulation Of Organelle Organization Cellular Response To Lipoprotein Particle Stimulus Basolateral Plasma Membrane Regulation Of Telomere Maintenance Via Telomerase Response To Xenobiotic Stimulus Cholesterol Binding Sphingolipid Floppase Activity Macrophage Fusion Positive Regulation Of Adaptive Immune Memory Response CD4-positive, Alpha-beta T Cell Costimulation Glial Cell Fate Determination Canonical Wnt Signaling Pathway Involved In Mesenchymal Stem Cell Differentiation Regulation Of Telomere Maintenance Via Telomere Lengthening Dihydrolipoyllysine-residue Succinyltransferase Activity Positive Regulation Of Actin Filament Bundle Assembly Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Positive Regulation Of Telomere Maintenance Response To Vitamin B3 Regulation Of Cell Communication Regulation Of High-density Lipoprotein Particle Assembly Positive Regulation Of High-density Lipoprotein Particle Assembly Regulation Of Intracellular Signal Transduction Apolipoprotein A-I Receptor Activity Regulation Of Protein-containing Complex Assembly Regulation Of Signaling Positive Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of MAPK Cascade Myoblast Fusion Involved In Skeletal Muscle Regeneration Mesenchymal Stem Cell Differentiation Oviduct Development Positive Regulation Of Determination Of Dorsal Identity Negative Regulation Of Mitotic Cell Cycle, Embryonic Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Beta-catenin-ICAT Complex Fungiform Papilla Formation Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Beta-catenin-TCF7L2 Complex Astrocyte-dopaminergic Neuron Signaling Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Renal Inner Medulla Development Scrib-APC-beta-catenin Complex	Glutamatergic Synapse PTW/PP1 Phosphatase Complex Regulation Of Protein Stability Branching Morphogenesis Of An Epithelial Tube Morphogenesis Of A Branching Structure Morphogenesis Of A Branching Epithelium Entrainment Of Circadian Clock By Photoperiod Protein Phosphatase 1 Binding Photoperiodism Entrainment Of Circadian Clock Postsynapse Protein Stabilization Postsynapse Organization Anatomical Structure Morphogenesis Animal Organ Development Transcription Elongation By RNA Polymerase II Organelle Organization Tube Morphogenesis DNA-templated Transcription Elongation Regulation Of Cell Population Proliferation Morphogenesis Of An Epithelium Circadian Regulation Of Gene Expression Glycogen Metabolic Process Chromosome Organization Cellular Response To Amino Acid Starvation Negative Regulation Of TORC1 Signaling Response To Amino Acid Starvation Energy Reserve Metabolic Process Polysaccharide Metabolic Process Regulation Of Multicellular Organismal Process Phosphatase Activity Embryonic Morphogenesis Extracellular Matrix Of Synaptic Cleft Tissue Morphogenesis Integrin-mediated Signaling Pathway DNA-templated Transcription Protein Dephosphorylation RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Protein Serine/threonine Phosphatase Activity Cell Division Negative Regulation Of TOR Signaling Regulation Of TORC1 Signaling Positive Regulation Of Macroautophagy Trophectodermal Cellular Morphogenesis Liver Morphogenesis Zonula Adherens Assembly HSP90-CDC37 Chaperone Complex Lung Development Positive Regulation Of Cellular Component Organization Glial Cell Differentiation
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