CD6 and GYG1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		CD6	GYG1
Description		CD6 molecule	glycogenin 1
Image
GO Annotations	Cellular Component	Immunological Synapse Extracellular Region Plasma Membrane Cell Surface Membrane T Cell Receptor Complex	Extracellular Region Nucleus Cytoplasm Cytosol Membrane Secretory Granule Lumen Lysosomal Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Lipopolysaccharide Binding Protein Binding Protein Kinase Binding Identical Protein Binding Lipoteichoic Acid Binding	Protein Binding Glycogenin Glucosyltransferase Activity Transferase Activity Glycosyltransferase Activity Manganese Ion Binding Protein Homodimerization Activity Metal Ion Binding
	Biological Process	Immunological Synapse Formation Adaptive Immune Response Immune System Process Acute Inflammatory Response To Antigenic Stimulus Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Lipopolysaccharide-mediated Signaling Pathway Response To Lipopolysaccharide Positive Regulation Of T Cell Proliferation Innate Immune Response Positive Regulation Of Cytokine Production Involved In Inflammatory Response	Glycogen Biosynthetic Process
Pathways			Glycogen synthesis Myoclonic epilepsy of Lafora Glycogen storage disease type XV (GYG1) Glycogen storage disease type 0 (muscle GYS1) Glycogen storage disease type II (GAA) Neutrophil degranulation Glycogen breakdown (glycogenolysis) Glycogen breakdown (glycogenolysis)
Drugs			Uridine diphosphate glucose Uridine-5'-Diphosphate
Diseases
GWAS		Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Gut microbiota (bacterial taxa) ( 27694959) Gut microbiota (functional units) ( 27694959) Inflammatory bowel disease ( 23128233 28067908) Lymphocyte count ( 32888494) Multiple sclerosis ( 19525953 21244703 21833088 24076602 31604244) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Diverticular disease ( 30177863)
Interacting Genes		5 interacting genes: ALCAM CD5 GYG1 NFE2L1 SDCBP	7 interacting genes: C1QTNF9 CD6 CMSS1 GYG2 GYS1 POM121 TRIM7
Entrez ID		923	2992
HPRD ID		01724	06805
Ensembl ID		ENSG00000013725	ENSG00000163754
Uniprot IDs		P30203 Q6AZ88 Q8N4Q7	P46976
PDB IDs		5A2E	3Q4S 3QVB 3RMV 3RMW 3T7M 3T7N 3T7O 3U2T 3U2U 3U2V 3U2W 3U2X 6EQJ 6EQL 7OVX 7Q0B 7Q0S 7Q12 7Q13 7ZBN 8CVX 8CVY 8CVZ
Enriched GO Terms of Interacting Partners?			Glycogen Biosynthetic Process Polysaccharide Biosynthetic Process Glycogen Metabolic Process Energy Reserve Metabolic Process Polysaccharide Metabolic Process Glycogen Synthase Activity, Transferring Glucose-1-phosphate Carbohydrate Biosynthetic Process Glycogenin Glucosyltransferase Activity Alpha-1,4-glucan Glucosyltransferase (UDP-glucose Donor) Activity Lipoteichoic Acid Binding Glycosyltransferase Activity Energy Derivation By Oxidation Of Organic Compounds D-glucose Binding
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