GYG1 and CD6

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		GYG1	CD6
Description		glycogenin 1	CD6 molecule
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Cytosol Membrane Secretory Granule Lumen Lysosomal Lumen Ficolin-1-rich Granule Lumen	Immunological Synapse Extracellular Region Plasma Membrane Cell Surface Membrane T Cell Receptor Complex
	Molecular Function	Protein Binding Glycogenin Glucosyltransferase Activity Transferase Activity Glycosyltransferase Activity Manganese Ion Binding Protein Homodimerization Activity Metal Ion Binding	Lipopolysaccharide Binding Protein Binding Protein Kinase Binding Identical Protein Binding Lipoteichoic Acid Binding
	Biological Process	Glycogen Biosynthetic Process	Immunological Synapse Formation Adaptive Immune Response Immune System Process Acute Inflammatory Response To Antigenic Stimulus Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Lipopolysaccharide-mediated Signaling Pathway Response To Lipopolysaccharide Positive Regulation Of T Cell Proliferation Innate Immune Response Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Pathways		Glycogen synthesis Myoclonic epilepsy of Lafora Glycogen storage disease type XV (GYG1) Glycogen storage disease type 0 (muscle GYS1) Glycogen storage disease type II (GAA) Neutrophil degranulation Glycogen breakdown (glycogenolysis) Glycogen breakdown (glycogenolysis)
Drugs		Uridine diphosphate glucose Uridine-5'-Diphosphate
Diseases
GWAS		Diverticular disease ( 30177863)	Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Gut microbiota (bacterial taxa) ( 27694959) Gut microbiota (functional units) ( 27694959) Inflammatory bowel disease ( 23128233 28067908) Lymphocyte count ( 32888494) Multiple sclerosis ( 19525953 21244703 21833088 24076602 31604244) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		7 interacting genes: C1QTNF9 CD6 CMSS1 GYG2 GYS1 POM121 TRIM7	5 interacting genes: ALCAM CD5 GYG1 NFE2L1 SDCBP
Entrez ID		2992	923
HPRD ID		06805	01724
Ensembl ID		ENSG00000163754	ENSG00000013725
Uniprot IDs		P46976	P30203 Q6AZ88 Q8N4Q7
PDB IDs		3Q4S 3QVB 3RMV 3RMW 3T7M 3T7N 3T7O 3U2T 3U2U 3U2V 3U2W 3U2X 6EQJ 6EQL 7OVX 7Q0B 7Q0S 7Q12 7Q13 7ZBN 8CVX 8CVY 8CVZ	5A2E
Enriched GO Terms of Interacting Partners?		Glycogen Biosynthetic Process Polysaccharide Biosynthetic Process Glycogen Metabolic Process Energy Reserve Metabolic Process Polysaccharide Metabolic Process Glycogen Synthase Activity, Transferring Glucose-1-phosphate Carbohydrate Biosynthetic Process Glycogenin Glucosyltransferase Activity Alpha-1,4-glucan Glucosyltransferase (UDP-glucose Donor) Activity Lipoteichoic Acid Binding Glycosyltransferase Activity Energy Derivation By Oxidation Of Organic Compounds D-glucose Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?