MTSS2 and SCAF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MTSS2	SCAF1
Description		MTSS I-BAR domain containing 2	SR-related CTD associated factor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ruffle Cytoplasm Plasma Membrane Cytoplasmic Side Of Plasma Membrane Actin Cytoskeleton Lamellipodium Cortical Actin Cytoskeleton Ruffle Membrane Cell Projection	Nucleus
	Molecular Function	Actin Binding Actin Monomer Binding GTPase Activator Activity Protein Binding Phospholipid Binding Phosphatidylinositol-4,5-bisphosphate Binding Small GTPase Binding	RNA Binding Protein Binding Protein Domain Specific Binding RNA Polymerase II C-terminal Domain Binding
	Biological Process	Plasma Membrane Organization Cell Projection Assembly Cellular Response To Platelet-derived Growth Factor Stimulus Membrane Organization Activation Of GTPase Activity Lamellipodium Organization	Transcription By RNA Polymerase II MRNA Processing RNA Splicing
Pathways
Drugs
Diseases
GWAS			Basal cell carcinoma ( 31174203) HDL cholesterol ( 30275531) Schizophrenia ( 25056061 29483656) Vitiligo ( 27723757)
Interacting Genes		2 interacting genes: ALAS1 SCAF1	10 interacting genes: BUD31 CIB1 GSC2 GSTP1 MEOX2 MTSS2 RTN4IP1 SRPK2 UBC UBQLN4
Entrez ID		92154	58506
HPRD ID		14289	11604
Ensembl ID		ENSG00000132613	ENSG00000126461
Uniprot IDs		Q765P7	Q9H7N4
PDB IDs
Enriched GO Terms of Interacting Partners?		Heme O Biosynthetic Process Hemoglobin Metabolic Process Response To Herbicide Response To Cobalt Ion 5-aminolevulinate Synthase Activity Response To Nickel Cation Response To Bile Acid Response To Platinum Ion Heme A Biosynthetic Process Protoporphyrinogen IX Biosynthetic Process Protoporphyrinogen IX Metabolic Process Hemoglobin Biosynthetic Process Heme B Biosynthetic Process RNA Polymerase II C-terminal Domain Binding Heme Biosynthetic Process Tetrapyrrole Biosynthetic Process Porphyrin-containing Compound Biosynthetic Process Response To Gonadotropin Erythrocyte Development Heme Metabolic Process Porphyrin-containing Compound Metabolic Process Pyridoxal Phosphate Binding Tetrapyrrole Metabolic Process Pigment Metabolic Process Macromolecule Biosynthetic Process Myeloid Cell Development Response To CAMP Cellular Response To Insulin Stimulus Response To Toxic Substance Response To Ethanol Response To Purine-containing Compound Acyltransferase Activity	Cellular Response To Growth Factor Stimulus Vesicle Dinitrosyl-iron Complex Binding S-nitrosoglutathione Binding Protein Serine/threonine Kinase Inhibitor Activity Nitric Oxide Storage Angiogenesis Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Male Germ Cell Proliferation Response To Growth Factor Negative Regulation Of Protein-containing Complex Disassembly
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