SCAF1 and MTSS2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SCAF1	MTSS2
Description		SR-related CTD associated factor 1	MTSS I-BAR domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Ruffle Cytoplasm Plasma Membrane Cytoplasmic Side Of Plasma Membrane Actin Cytoskeleton Lamellipodium Cortical Actin Cytoskeleton Ruffle Membrane Cell Projection
	Molecular Function	RNA Binding Protein Binding Protein Domain Specific Binding RNA Polymerase II C-terminal Domain Binding	Actin Binding Actin Monomer Binding GTPase Activator Activity Protein Binding Phospholipid Binding Phosphatidylinositol-4,5-bisphosphate Binding Small GTPase Binding
	Biological Process	Transcription By RNA Polymerase II MRNA Processing RNA Splicing	Plasma Membrane Organization Cell Projection Assembly Cellular Response To Platelet-derived Growth Factor Stimulus Membrane Organization Activation Of GTPase Activity Lamellipodium Organization
Pathways
Drugs
Diseases
GWAS		Basal cell carcinoma ( 31174203) HDL cholesterol ( 30275531) Schizophrenia ( 25056061 29483656) Vitiligo ( 27723757)
Interacting Genes		10 interacting genes: BUD31 CIB1 GSC2 GSTP1 MEOX2 MTSS2 RTN4IP1 SRPK2 UBC UBQLN4	2 interacting genes: ALAS1 SCAF1
Entrez ID		58506	92154
HPRD ID		11604	14289
Ensembl ID		ENSG00000126461	ENSG00000132613
Uniprot IDs		Q9H7N4	Q765P7
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Growth Factor Stimulus Vesicle Dinitrosyl-iron Complex Binding S-nitrosoglutathione Binding Protein Serine/threonine Kinase Inhibitor Activity Nitric Oxide Storage Angiogenesis Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Male Germ Cell Proliferation Response To Growth Factor Negative Regulation Of Protein-containing Complex Disassembly	Heme O Biosynthetic Process Hemoglobin Metabolic Process Response To Herbicide Response To Cobalt Ion 5-aminolevulinate Synthase Activity Response To Nickel Cation Response To Bile Acid Response To Platinum Ion Heme A Biosynthetic Process Protoporphyrinogen IX Biosynthetic Process Protoporphyrinogen IX Metabolic Process Hemoglobin Biosynthetic Process Heme B Biosynthetic Process RNA Polymerase II C-terminal Domain Binding Heme Biosynthetic Process Tetrapyrrole Biosynthetic Process Porphyrin-containing Compound Biosynthetic Process Response To Gonadotropin Erythrocyte Development Heme Metabolic Process Porphyrin-containing Compound Metabolic Process Pyridoxal Phosphate Binding Tetrapyrrole Metabolic Process Pigment Metabolic Process Macromolecule Biosynthetic Process Myeloid Cell Development Response To CAMP Cellular Response To Insulin Stimulus Response To Toxic Substance Response To Ethanol Response To Purine-containing Compound Acyltransferase Activity
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