RRP9 and STAB1

		RRP9	STAB1
Description		ribosomal RNA processing 9, U3 small nucleolar RNA binding protein	stabilin 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Box C/D Methylation Guide SnoRNP Complex Small-subunit Processome Ribonucleoprotein Complex	Plasma Membrane Membrane Endocytic Vesicle Membrane
	Molecular Function	RNA Binding Protein Binding SnoRNA Binding U3 SnoRNA Binding	Low-density Lipoprotein Particle Receptor Activity Scavenger Receptor Activity Calcium Ion Binding Protein Binding Hyaluronic Acid Binding Protein-disulfide Reductase Activity Low-density Lipoprotein Particle Binding
	Biological Process	RRNA Processing Ribosomal Small Subunit Biogenesis	Endocytosis Receptor-mediated Endocytosis Inflammatory Response Cell Adhesion Cell-cell Signaling Negative Regulation Of Angiogenesis Defense Response To Bacterium
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol	Scavenging by Class H Receptors
Drugs
Diseases
GWAS			A body shape index ( 34021172) Adiponectin levels ( 31178129) Apolipoprotein A1 levels ( 32203549) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972 31043756) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) Colon cancer ( 33632709) Cortical surface area (MOSTest) ( 32665545) Distal colorectal cancer ( 33632709) Diverticular disease ( 30177863) HDL cholesterol ( 24097068) HDL cholesterol levels ( 28334899) Height ( 31562340) Hematocrit ( 27863252) Hodgkin's lymphoma ( 34216518) Intelligence (MTAG) ( 29326435) Iron status biomarkers (ferritin levels) ( 33536631) Parkinson's disease ( 28892059) Schizophrenia ( 29483656 25056061 23974872) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urinary albumin-to-creatinine ratio ( 31511532) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-hip ratio ( 20935629) Waist-to-hip ratio adjusted for BMI ( 34021172) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		4 interacting genes: CSNK2A1 RAP2A SIRT7 SMURF1	8 interacting genes: CHID1 DYRK1A GGA1 GGA2 GGA3 NUFIP2 ORC5 PIK3R2
Entrez ID		9136	23166
HPRD ID		08827	09778
Ensembl ID		ENSG00000114767	ENSG00000010327
Uniprot IDs		O43818	Q9NY15
PDB IDs		4J0W 4JXM 7MQ8 7MQ9 7MQA
Enriched GO Terms of Interacting Partners?		Protein Targeting To Vacuole Involved In Autophagy Regulation Of Cellular Response To Stress Protein Localization To Vacuole Establishment Of Protein Localization To Vacuole Protein Targeting To Vacuole Vasoconstriction Of Artery Involved In Ischemic Response To Lowering Of Systemic Arterial Blood Pressure Histone H3K18 Deacetylase Activity, NAD-dependent NAD-dependent Protein-lysine Depropionylase Activity Protein Deglutarylation Protein-succinyllysine Desuccinylase Activity Protein Depropionylation Nucleolus Organizer Region Protein-glutaryllysine Deglutarylase Activity Engulfment Of Target By Autophagosome Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Positive Regulation Of Cell Growth Regulation Of Ubiquitin-dependent Protein Catabolic Process Vacuolar Transport Intracellular Signal Transduction Positive Regulation Of Aggrephagy Positive Regulation Of Microvillus Assembly Protein Targeting Sulfatide Binding Activin Receptor Binding Regulation Of DNA Repair Regulation Of Anatomical Structure Morphogenesis Endolysosome ATF6-mediated Unfolded Protein Response NAD-dependent Protein Lysine Deacetylase Activity Substrate Localization To Autophagosome Positive Regulation Of Growth Positive Regulation Of RRNA Processing R-loop Processing Rap Protein Signal Transduction Regulation Of Microvillus Assembly Sarcoplasmic Reticulum Lumen Wnt Signaling Pathway Double-strand Break Repair Via Classical Nonhomologous End Joining Aggrephagy Regulation Of Cellular Component Organization Signal Transduction Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Establishment Of Protein Localization To Organelle Positive Regulation Of Systemic Arterial Blood Pressure Low-density Lipoprotein Particle Receptor Activity Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Regulation Of RRNA Processing Protein Deacetylation Protein Methyltransferase Activity	Golgi To Plasma Membrane Protein Transport Protein Localization To Cell Surface Establishment Of Protein Localization To Membrane Establishment Of Protein Localization To Plasma Membrane Trans-Golgi Network Golgi To Plasma Membrane Transport Ubiquitin Binding Post-Golgi Vesicle-mediated Transport Phosphatidylinositol Binding Vesicle-mediated Transport To The Plasma Membrane Localization Within Membrane Intracellular Protein Transport Protein Localization To Plasma Membrane Early Endosome Membrane Regulation Of Amyloid-beta Formation Protein Transport Protein Localization To Cell Periphery Regulation Of Amyloid Precursor Protein Catabolic Process Histone H3T45 Kinase Activity Establishment Of Protein Localization Endosome Membrane Small GTPase Binding Golgi Vesicle Transport Protein Localization To Membrane Regulation Of Amide Metabolic Process Actin Filament Ribonucleoprotein Complex Regulation Of Supramolecular Fiber Organization Endoplasmic Reticulum Signal Peptide Binding Regulation Of Protein-containing Complex Assembly Negative Regulation Of Heterochromatin Formation Negative Regulation Of Protein-containing Complex Assembly Regulation Of Neurofibrillary Tangle Assembly Splicing Factor Binding Origin Recognition Complex Regulation Of Actin Filament Polymerization Regulation Of Actin Polymerization Or Depolymerization Intracellular Protein Localization Regulation Of Actin Filament Length 1-phosphatidylinositol-3-kinase Regulator Activity Signal Recognition Particle SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition Box C/D Methylation Guide SnoRNP Complex Regulation Of Microvillus Length Anion Binding Positive Regulation Of Lysosomal Protein Catabolic Process Regulation Of Cytoskeleton Organization Negative Regulation Of Cytoskeleton Organization Negative Regulation Of Supramolecular Fiber Organization 7S RNA Binding
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