TMEM129

Description		transmembrane protein 129, E3 ubiquitin ligase
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Response To Unfolded Protein Protein Ubiquitination Retrograde Protein Transport, ER To Cytosol ERAD Pathway
Pathways		E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS		Bladder cancer ( 20972438 24163127) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Type 1 diabetes ( 33830302) Urinary bladder cancer ( 20348956) Walking pace ( 33128006)
Interacting Genes		6 interacting genes: DLC1 MSANTD3 PDGFRL PSMD4 UBE2D1 UBE2D3
Entrez ID		92305
HPRD ID		14290
Ensembl ID		ENSG00000168936
Uniprot IDs		A0AVI4
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Platelet-derived Growth Factor Beta-receptor Activity Platelet-derived Growth Factor Receptor Activity Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Modification-dependent Protein Catabolic Process Negative Regulation Of BMP Signaling Pathway Protein K48-linked Ubiquitination Regulation Of BMP Signaling Pathway Hindbrain Morphogenesis Negative Regulation Of Cellular Response To Growth Factor Stimulus Protein Catabolic Process Platelet Activating Factor Receptor Activity Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Platelet-derived Growth Factor Receptor-beta Signaling Pathway Ubiquitin-protein Transferase Activity Macromolecule Catabolic Process Proteasome Regulatory Particle, Base Subcomplex Protein Polyubiquitination Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Tagcloud ?