RNF187

Description		ring finger protein 187
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Positive Regulation Of Cell Population Proliferation Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of DNA-templated Transcription Protein Autoubiquitination Protein K48-linked Ubiquitination
Pathways
Drugs
Diseases
GWAS		Cerebrospinal fluid sTREM-2 levels ( 31708768) Tuberculosis ( 24057671)
Interacting Genes		7 interacting genes: JUN PRMT1 TP53 TRIM7 XRN1 ZNF417 ZNF835
Entrez ID		149603
HPRD ID		19493
Ensembl ID		ENSG00000168159
Uniprot IDs		Q5TA31
PDB IDs		7OW2
Enriched GO Terms of Interacting Partners?		Negative Regulation Of DNA Metabolic Process Viral Process General Transcription Initiation Factor Binding Negative Regulation Of Telomere Maintenance Via Telomerase Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Enzyme Binding GATOR1 Complex Binding Transcription Repressor Complex Positive Regulation Of DNA-templated Transcription Initiation Regulation Of MiRNA Transcription Positive Regulation Of MiRNA Metabolic Process Positive Regulation Of MiRNA Transcription RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of Helicase Activity Negative Regulation Of G1 To G0 Transition Regulation Of Telomere Maintenance Via Telomere Lengthening Cellular Response To Puromycin Cellular Response To Cycloheximide Negative Regulation Of Chromosome Organization DNA Binding Regulation Of DNA-templated Transcription Initiation Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of MiRNA Metabolic Process Regulation Of Fibroblast Proliferation Regulation Of DNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of DNA Metabolic Process Leading Edge Cell Differentiation Transforming Growth Factor Beta Receptor Signaling Pathway Oligodendrocyte Apoptotic Process Negative Regulation Of Pentose-phosphate Shunt Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Regulation Of Telomere Maintenance Nucleus Negative Regulation Of Macromolecule Metabolic Process Cellular Response To Anisomycin Negative Regulation Of Fermentation Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Oxidative Stress-induced Premature Senescence Glucose Catabolic Process To Lactate Via Pyruvate Germ Cell Nucleus Cellular Response To Actinomycin D Negative Regulation Of Protein Metabolic Process
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