TP53I13 and KLHL8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TP53I13	KLHL8
Description		tumor protein p53 inducible protein 13	kelch like family member 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane	Nucleoplasm Cytoplasm Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding	Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Response To Xenobiotic Stimulus Response To UV Negative Regulation Of Cell Cycle	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545)	Alanine aminotransferase levels ( 33547301 33339817) Alanine transaminase levels ( 29403010) Aspartate aminotransferase levels ( 29403010 33547301 33339817) Bulimia nervosa ( 23568457) Eyebrow thickness ( 26926045) HDL cholesterol levels ( 28334899) Rosacea symptom severity ( 29771307) Total cholesterol levels ( 30275531) Triglyceride levels ( 28334899 29403010 33339817) Triglycerides ( 20686565 25961943 24097068)
Interacting Genes		2 interacting genes: KLHL8 TRIM7	13 interacting genes: ARMC9 ATXN1 CA8 COIL MAPK9 PNMT PPM1F RAPSN RLBP1 SULT2B1 TEX101 TP53I13 USP7
Entrez ID		90313	57563
HPRD ID		14267	13928
Ensembl ID		ENSG00000167543	ENSG00000145332
Uniprot IDs		Q8NBR0	B3KY78 Q68DU9 Q9P2G9
PDB IDs
Enriched GO Terms of Interacting Partners?		Kinociliary Basal Body Opsin Transport Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Dendrite Terminus Opsin Binding Intraciliary Transport Particle Protein Ubiquitination Protein Modification By Small Protein Conjugation Establishment Of Planar Polarity Establishment Of Apical/basal Cell Polarity Cardiac Muscle Cell Differentiation Establishment Of Monopolar Cell Polarity Photoreceptor Cell Outer Segment Organization Intraciliary Transport Particle B Manchette Protein Localization To Golgi Apparatus Establishment Of Epithelial Cell Polarity Establishment Of Epithelial Cell Apical/basal Polarity Establishment Or Maintenance Of Monopolar Cell Polarity Cochlea Development Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Non-motile Cilium Polarized Epithelial Cell Differentiation Positive Regulation Of Cilium Assembly Centrosome Localization Intraciliary Anterograde Transport Inner Ear Receptor Cell Stereocilium Organization Post-translational Protein Modification Ciliary Tip Regulation Of Autophagosome Assembly Photoreceptor Connecting Cilium Stereocilium Cis-Golgi Network Cardiocyte Differentiation Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Intraciliary Transport Ciliary Base Visual Learning Establishment Or Maintenance Of Apical/basal Cell Polarity Cul3-RING Ubiquitin Ligase Complex Visual Behavior Regulation Of Vacuole Organization Protein Localization To Cilium Microvillus Photoreceptor Outer Segment
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