KLHL8 and TP53I13

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KLHL8	TP53I13
Description		kelch like family member 8	tumor protein p53 inducible protein 13
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cul3-RING Ubiquitin Ligase Complex	Cytoplasm Plasma Membrane Membrane
	Molecular Function	Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity	Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Response To Xenobiotic Stimulus Response To UV Negative Regulation Of Cell Cycle
Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301 33339817) Alanine transaminase levels ( 29403010) Aspartate aminotransferase levels ( 29403010 33547301 33339817) Bulimia nervosa ( 23568457) Eyebrow thickness ( 26926045) HDL cholesterol levels ( 28334899) Rosacea symptom severity ( 29771307) Total cholesterol levels ( 30275531) Triglyceride levels ( 28334899 29403010 33339817) Triglycerides ( 20686565 25961943 24097068)	Brain morphology (MOSTest) ( 32665545)
Interacting Genes		13 interacting genes: ARMC9 ATXN1 CA8 COIL MAPK9 PNMT PPM1F RAPSN RLBP1 SULT2B1 TEX101 TP53I13 USP7	2 interacting genes: KLHL8 TRIM7
Entrez ID		57563	90313
HPRD ID		13928	14267
Ensembl ID		ENSG00000145332	ENSG00000167543
Uniprot IDs		B3KY78 Q68DU9 Q9P2G9	Q8NBR0
PDB IDs
Enriched GO Terms of Interacting Partners?			Kinociliary Basal Body Opsin Transport Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Dendrite Terminus Opsin Binding Intraciliary Transport Particle Protein Ubiquitination Protein Modification By Small Protein Conjugation Establishment Of Planar Polarity Establishment Of Apical/basal Cell Polarity Cardiac Muscle Cell Differentiation Establishment Of Monopolar Cell Polarity Photoreceptor Cell Outer Segment Organization Intraciliary Transport Particle B Manchette Protein Localization To Golgi Apparatus Establishment Of Epithelial Cell Polarity Establishment Of Epithelial Cell Apical/basal Polarity Establishment Or Maintenance Of Monopolar Cell Polarity Cochlea Development Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Non-motile Cilium Polarized Epithelial Cell Differentiation Positive Regulation Of Cilium Assembly Centrosome Localization Intraciliary Anterograde Transport Inner Ear Receptor Cell Stereocilium Organization Post-translational Protein Modification Ciliary Tip Regulation Of Autophagosome Assembly Photoreceptor Connecting Cilium Stereocilium Cis-Golgi Network Cardiocyte Differentiation Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Intraciliary Transport Ciliary Base Visual Learning Establishment Or Maintenance Of Apical/basal Cell Polarity Cul3-RING Ubiquitin Ligase Complex Visual Behavior Regulation Of Vacuole Organization Protein Localization To Cilium Microvillus Photoreceptor Outer Segment
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