SGCE and CWC15

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		SGCE	CWC15
Description		sarcoglycan epsilon	CWC15 spliceosome associated protein
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Sarcoglycan Complex Membrane Dendrite Dendrite Membrane Sarcolemma Cell Projection	Prp19 Complex Nucleus Nucleoplasm Spliceosomal Complex Mitochondrion Nuclear Speck U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function		RNA Binding Protein Binding
	Biological Process	Cell-matrix Adhesion Muscle Organ Development	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing MRNA Cis Splicing, Via Spliceosome
Pathways		Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)	mRNA Splicing - Major Pathway
Drugs
Diseases		Primary torsion dystonia (PTD)
GWAS			Attention deficit hyperactivity disorder and conduct disorder ( 18951430) LDL cholesterol levels in HIV infection ( 33109212)
Interacting Genes		4 interacting genes: ARIH2 CWC15 KEAP1 PPP1CC	5 interacting genes: APP LRRK1 PRNP RBM17 SGCE
Entrez ID		8910	51503
HPRD ID		04999	13703
Ensembl ID		ENSG00000127990	ENSG00000150316
Uniprot IDs		A0A0S2Z4P5 A0A2R8Y448 A0A2R8Y5J3 A0A2R8YGQ3 B4DP78 C9JR67 E9PEH6 O43556	Q9P013
PDB IDs			5MQF 5XJC 5YZG 5Z56 5Z57 5Z58 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM 7AAV 7ABF 7ABG 7ABI 7DVQ 7QTT 7W59 7W5A 7W5B 8C6J 8CH6 8I0P 8I0R 8I0S 8I0T 8I0U 8I0V 8I0W 8RO2 9FMD
Enriched GO Terms of Interacting Partners?			Neuron Projection Maintenance Regulation Of Dendritic Spine Maintenance Negative Regulation Of Long-term Synaptic Potentiation Intracellular Copper Ion Homeostasis Copper Ion Homeostasis Cellular Response To Copper Ion Molecular Function Activator Activity Dendrite Membrane Response To Copper Ion Neuron Projection Organization Regulation Of Long-term Synaptic Potentiation Regulation Of Amyloid Precursor Protein Catabolic Process Cellular Response To Amyloid-beta Positive Regulation Of Calcium-mediated Signaling Response To Amyloid-beta Myeloid Cell Development Positive Regulation Of Neuron Apoptotic Process Dendrite Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Calcium-mediated Signaling Type 8 Metabotropic Glutamate Receptor Binding Protein-folding Chaperone Binding Regulation Of Type II Interferon Production Memory Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import PTB Domain Binding Regulation Of Calcium Ion Transmembrane Transport Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Postsynapse Organization Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Cellular Response To Metal Ion Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Hemopoiesis Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Type 5 Metabotropic Glutamate Receptor Binding
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