SGCE and CYP3A7

		SGCE	CYP3A7
Description		sarcoglycan epsilon	cytochrome P450 family 3 subfamily A member 7
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Sarcoglycan Complex Membrane Dendrite Dendrite Membrane Sarcolemma Cell Projection	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function		Monooxygenase Activity Iron Ion Binding Steroid Hydroxylase Activity Retinoic Acid 4-hydroxylase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Reduced Flavin Or Flavoprotein As One Donor, And Incorporation Of One Atom Of Oxygen Oxygen Binding Heme Binding Metal Ion Binding Testosterone 6-beta-hydroxylase Activity All-trans Retinoic Acid 18-hydroxylase Activity Estrogen 16-alpha-hydroxylase Activity Estrogen 2-hydroxylase Activity
	Biological Process	Cell-matrix Adhesion Muscle Organ Development	Lipid Hydroxylation Lipid Metabolic Process Steroid Biosynthetic Process Xenobiotic Metabolic Process Steroid Metabolic Process Estrogen Metabolic Process Retinol Metabolic Process Retinoic Acid Metabolic Process Oxidative Demethylation
Pathways		Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)	Xenobiotics
Drugs			Cannabidiol Diacerein Nabiximols
Diseases		Primary torsion dystonia (PTD)
GWAS			Endometrial cancer ( 30093612) Estradiol levels ( 34255042) Serum metabolite levels ( 23093944 33031748) Sex hormone levels ( 26014426) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)
Interacting Genes		4 interacting genes: ARIH2 CWC15 KEAP1 PPP1CC
Entrez ID		8910	1551
HPRD ID		04999	05630
Ensembl ID		ENSG00000127990	ENSG00000160870
Uniprot IDs		A0A0S2Z4P5 A0A2R8Y448 A0A2R8Y5J3 A0A2R8YGQ3 B4DP78 C9JR67 E9PEH6 O43556	P24462
PDB IDs			7MK8
Enriched GO Terms of Interacting Partners?			Sarcoglycan Complex Dystrophin-associated Glycoprotein Complex Dendrite Membrane Muscle Organ Development Sarcolemma Muscle Structure Development Cell-substrate Adhesion Cell-matrix Adhesion
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