CYP3A7

Description		cytochrome P450 family 3 subfamily A member 7
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Monooxygenase Activity Iron Ion Binding Steroid Hydroxylase Activity Retinoic Acid 4-hydroxylase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Reduced Flavin Or Flavoprotein As One Donor, And Incorporation Of One Atom Of Oxygen Oxygen Binding Heme Binding Metal Ion Binding Testosterone 6-beta-hydroxylase Activity All-trans Retinoic Acid 18-hydroxylase Activity Estrogen 16-alpha-hydroxylase Activity Estrogen 2-hydroxylase Activity
	Biological Process	Lipid Hydroxylation Lipid Metabolic Process Steroid Biosynthetic Process Xenobiotic Metabolic Process Steroid Metabolic Process Estrogen Metabolic Process Retinol Metabolic Process Retinoic Acid Metabolic Process Oxidative Demethylation
Pathways		Xenobiotics
Drugs		Cannabidiol Diacerein Nabiximols
Diseases
GWAS		Endometrial cancer ( 30093612) Estradiol levels ( 34255042) Serum metabolite levels ( 23093944 33031748) Sex hormone levels ( 26014426) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)
Novel Interacting Genes		1 novel interacting genes: SGCE
Interacting Genes
Entrez ID		1551
HPRD ID		05630
Ensembl ID		ENSG00000160870
Uniprot IDs		P24462
PDB IDs		7MK8
Enriched GO Terms of Interacting Partners?		Sarcoglycan Complex Dystrophin-associated Glycoprotein Complex Dendrite Membrane Muscle Organ Development Sarcolemma Muscle Structure Development Cell-substrate Adhesion Cell-matrix Adhesion
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