GALR2 and GAL

Number of citations of the paper that reports this interaction (PubMedID 9685625)
0

Data Source:
HPRD (in vivo)

		GALR2	GAL
Description		galanin receptor 2	galanin and GMAP prepropeptide
Image
GO Annotations	Cellular Component	Plasma Membrane Cilium Membrane	Extracellular Region Extracellular Space Secretory Granule Neuronal Cell Body
	Molecular Function	G Protein-coupled Receptor Activity Galanin Receptor Activity Protein Binding Peptide Hormone Binding Neuropeptide Binding	Galanin Receptor Activity Hormone Activity Neuropeptide Hormone Activity Protein Binding Galanin Receptor Binding Type 1 Galanin Receptor Binding Type 2 Galanin Receptor Binding Type 3 Galanin Receptor Binding
	Biological Process	Muscle Contraction Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Learning Or Memory Feeding Behavior Neuron Projection Development Inositol Phosphate Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Phosphatidylinositol Metabolic Process Galanin-activated Signaling Pathway	Neuropeptide Signaling Pathway Nervous System Development Feeding Behavior Negative Regulation Of Cell Population Proliferation Response To Xenobiotic Stimulus Protein Kinase A Signaling Insulin Secretion Regulation Of Glucocorticoid Metabolic Process Response To Insulin Response To Immobilization Stress Positive Regulation Of Apoptotic Process Response To Estrogen Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Lymphocyte Proliferation Positive Regulation Of Cortisol Secretion Positive Regulation Of Timing Of Catagen Parental Behavior Positive Regulation Of Large Conductance Calcium-activated Potassium Channel Activity
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events	Peptide ligand-binding receptors G alpha (i) signalling events
Drugs
Diseases
GWAS			Femoral neck section modulus ( 30888730) Height ( 28552196) Serum metabolite levels ( 33031748)
Interacting Genes		2 interacting genes: GAL GNAQ	7 interacting genes: ASPH GALR1 GALR2 GPR151 SGTA UBQLN1 UBQLN2
Entrez ID		8811	51083
HPRD ID		04735	00658
Ensembl ID		ENSG00000182687	ENSG00000069482
Uniprot IDs		O43603	P22466
PDB IDs		7WQ4 7XBD 7XJK 7XJL	7S3O 7S3Q 7S3R 7WQ3 7WQ4 7XBD 7XJJ 7XJK 8DHZ 8DJ4
Enriched GO Terms of Interacting Partners?		Neuropeptide Signaling Pathway Positive Regulation Of Large Conductance Calcium-activated Potassium Channel Activity Type 1 Galanin Receptor Binding Galanin Receptor Binding Type 2 Galanin Receptor Binding Type 3 Galanin Receptor Binding Adenylate Cyclase-activating G Protein-coupled CAMP Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Glutamate Receptor Signaling Pathway Positive Regulation Of Timing Of Catagen Positive Regulation Of Cortisol Secretion Regulation Of Timing Of Catagen Galanin Receptor Activity Phospholipase C-activating Serotonin Receptor Signaling Pathway Response To Hormone Regulation Of Cell Activation Protein Kinase A Signaling Positive Regulation Of Hair Follicle Development Regulation Of Glucocorticoid Metabolic Process Phototransduction, Visible Light Parental Behavior G Protein-coupled Glutamate Receptor Signaling Pathway Guanyl Nucleotide Binding G Protein-coupled Receptor Signaling Pathway Cellular Response To Acidic PH Response To Acidic PH G Protein-coupled Acetylcholine Receptor Signaling Pathway Cellular Response To PH G-protein Beta/gamma-subunit Complex Binding Detection Of Visible Light Entrainment Of Circadian Clock Response To Prostaglandin E G Protein-coupled Serotonin Receptor Signaling Pathway Enzyme Regulator Activity Response To Immobilization Stress Positive Regulation Of Potassium Ion Transmembrane Transport Regulation Of Hair Cycle Regulation Of Hair Follicle Development Positive Regulation Of Cation Channel Activity Postsynaptic Cytosol Neuropeptide Hormone Activity Heterotrimeric G-protein Complex Reproductive Behavior Positive Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Potassium Ion Transport Regulation Of Hormone Metabolic Process Response To PH Positive Regulation Of Transporter Activity Phototransduction Acetylcholine Receptor Signaling Pathway Insulin Secretion	Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Positive Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Proteolysis Galanin Receptor Activity Regulation Of Response To Endoplasmic Reticulum Stress ERAD Pathway Regulation Of Proteolysis Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Cytosolic Calcium Ion Concentration Neuropeptide Binding Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Peptide Hormone Binding Response To Endoplasmic Reticulum Stress Polyubiquitin Modification-dependent Protein Binding Regulation Of Transport Positive Regulation Of Protein Metabolic Process Positive Regulation Of Macromolecule Metabolic Process G Protein-coupled Receptor Activity Regulation Of Protein Catabolic Process Positive Regulation Of Metabolic Process Galanin-activated Signaling Pathway Negative Regulation Of Store-operated Calcium Channel Activity Regulation Of Transmembrane Transporter Activity Regulation Of Monoatomic Ion Transmembrane Transporter Activity Autophagosome Autophagosome Assembly Proteasomal Protein Catabolic Process Neuropeptide Signaling Pathway Autophagosome Organization Peptidyl-aspartic Acid 3-dioxygenase Activity TRC Complex Negative Regulation Of G Protein-coupled Receptor Internalization Regulation Of Cellular Response To Stress Positive Regulation Of Catabolic Process Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Protein Catabolic Process Regulation Of Calcium Ion Transmembrane Transport Membrane Positive Regulation Of Cortisol Secretion BAT3 Complex Binding Negative Regulation Of Clathrin-dependent Endocytosis Regulation Of Protein Metabolic Process Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Plasma Membrane Activation Of Store-operated Calcium Channel Activity Proteolysis Involved In Protein Catabolic Process
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