MATN3

Name	matrilin 3
Structure	No pdb structure
Interactors	6 interactors: INCA1 KRTAP10-8 MATN1 MATN4 NOTCH2NLA TCF4
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Lumen Extracellular Matrix Matrilin Complex
	Molecular Function	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding
	Biological Process	Skeletal System Development Extracellular Matrix Organization Cartilage Development
Pathways	ECM proteoglycans Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Diseases	SEMD, Matrilin type; Spondyloepimetaphyseal dysplasia Multiple epiphyseal dysplasia (MED)
GWAS	Waist circumference adjusted for body mass index ( 34021172 ) Waist-hip index ( 34021172 )
Entrez ID	4148
HPRD ID	03661
Ensembl ID	ENSG00000132031
Uniprot IDs	O15232
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Matrilin Complex Growth Plate Cartilage Chondrocyte Morphogenesis Calcium Ion Binding Beta-catenin-TCF7L2 Complex TFIIB-class Transcription Factor Binding Extracellular Structure Organization Extracellular Matrix Organization Cartilage Morphogenesis Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Cyclin-dependent Protein Kinase Activity Beta-catenin-TCF Complex Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity