GGACT and PLAAT5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		GGACT	PLAAT5
Description		gamma-glutamylamine cyclotransferase	phospholipase A and acyltransferase 5
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Cytoplasm Cytosol
	Molecular Function	Protein Binding Lyase Activity Gamma-glutamylaminecyclotransferase Activity	Phospholipase A2 Activity Protein Binding Phospholipase A1 Activity N-acyltransferase Activity Transferase Activity Acyltransferase Activity Hydrolase Activity
	Biological Process	Modified Amino Acid Catabolic Process	Lipid Metabolic Process N-acylphosphatidylethanolamine Metabolic Process
Pathways			Acyl chain remodelling of PE
Drugs		Formic acid
Diseases
GWAS		Refractive error ( 32231278) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		3 interacting genes: LDB2 PLAAT5 ZBED1	6 interacting genes: - APP CLK1 GGACT GOLGA2 HOMER3
Entrez ID		87769	117245
HPRD ID		14263	13672
Ensembl ID		ENSG00000134864	ENSG00000168004
Uniprot IDs		Q9BVM4	B4DY88 Q8NE88 Q96KN8
PDB IDs		3JUB 3JUC 3JUD
Enriched GO Terms of Interacting Partners?		Transcription Coregulator Activity Protein Autosumoylation LIM Domain Binding N-acylphosphatidylethanolamine Metabolic Process N-acyltransferase Activity SUMO Ligase Activity Host-mediated Suppression Of Viral Genome Replication	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Glutamate Receptor Signaling Pathway Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Protein Tetramerization Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Calcium-mediated Signaling Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization G Protein-coupled Glutamate Receptor Binding Gamma-glutamylaminecyclotransferase Activity Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of Protein Glycosylation Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Regulation Of Spontaneous Synaptic Transmission Protein Homooligomerization NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Golgi Disassembly Axon Choice Point Recognition Regulation Of Calcium Ion Transport Regulation Of Protein Glycosylation Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Protein Complex Oligomerization Cellular Response To Manganese Ion Importin-alpha Family Protein Binding Golgi Ribbon Formation Negative Regulation Of Blood Circulation
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