STX10 and CXorf66

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		STX10	CXorf66
Description		syntaxin 10	chromosome X open reading frame 66
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Trans-Golgi Network Cytosol Endomembrane System Membrane Synaptic Vesicle Membrane Organelle Membrane SNARE Complex Vesicle Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm	Membrane
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding	Protein Binding
	Biological Process	Intracellular Protein Transport Vesicle Fusion Protein Transport Vesicle-mediated Transport Regulation Of Protein Localization Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport Vesicle Docking
Pathways		Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Venous thromboembolism ( 31420334)
Interacting Genes		6 interacting genes: COQ8A CXorf66 STX1A STX4 TMEM101 USP2-AS1	12 interacting genes: AQP6 ASPH EMD ERGIC3 LAT POMGNT1 RPRM RTP2 STX10 TMEM31 TMX2 YIPF6
Entrez ID		8677	347487
HPRD ID		04791	18139
Ensembl ID		ENSG00000104915	ENSG00000203933
Uniprot IDs		O60499 Q5U8S2 X6R2W0	Q5JRM2
PDB IDs		4DND
Enriched GO Terms of Interacting Partners?		SNARE Complex Assembly SNARE Complex Positive Regulation Of Regulated Secretory Pathway SNAP Receptor Activity SNARE Binding Vesicle Docking Schaffer Collateral - CA1 Synapse Membrane Docking Neurotransmitter Transport Positive Regulation Of Exocytosis Vesicle Fusion Myosin Head/neck Binding Organelle Localization By Membrane Tethering Sphingomyelin Phosphodiesterase Activator Activity Organelle Membrane Fusion Positive Regulation Of Eosinophil Degranulation Storage Vacuole Positive Regulation Of Synaptic Transmission Organelle Fusion Positive Regulation Of Norepinephrine Secretion Regulation Of Regulated Secretory Pathway Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Neuron Projection Membrane Membrane Fusion Regulation Of Insulin Secretion Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Lateral Loop Regulation Of Exocytosis Regulation Of Peptide Hormone Secretion Exocytosis Cornified Envelope Assembly Myelin Sheath Adaxonal Region Extrinsic Component Of Mitochondrial Inner Membrane ATP-dependent Protein Binding Response To Gravity Chloride Channel Inhibitor Activity Actomyosin Regulation Of Hormone Secretion Regulation Of Protein Secretion Endomembrane System Regulation Of Synaptic Vesicle Priming Synaptic Vesicle Docking Regulation Of Norepinephrine Secretion Positive Regulation Of Catecholamine Secretion Positive Regulation Of Secretion By Cell Vesicle Organization Positive Regulation Of Secretion Calcium Channel Inhibitor Activity Specific Granule	Membrane Cortical Endoplasmic Reticulum Positive Regulation Of Intracellular Protein Transport Regulation Of Intracellular Protein Transport Positive Regulation Of Intracellular Transport COPII-coated ER To Golgi Transport Vesicle PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Nitrate Transmembrane Transport Peptidyl-aspartic Acid 3-dioxygenase Activity Regulation Of Intracellular Transport Positive Regulation Of Establishment Of Protein Localization Positive Regulation Of Protein Transport TMEM240-body Golgi Membrane Golgi Apparatus Golgi Vesicle Transport TCR Signalosome Retrograde Transporter Complex, Golgi To ER Beta-1,3-galactosyl-O-glycosyl-glycoprotein Beta-1,3-N-acetylglucosaminyltransferase Activity Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Endoplasmic Reticulum Detection Of Chemical Stimulus Regulation Of Protein Localization Cellular Localization Transporter Complex Olfactory Receptor Binding Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Activation Of Store-operated Calcium Channel Activity Positive Regulation Of Protein Localization Regulation Of Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Localization Of Cell Positive Regulation Of Store-operated Calcium Channel Activity Reactive Gliosis
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