ADAM11 and STC2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ADAM11	STC2
Gene Name		ADAM metallopeptidase domain 11	stanniocalcin 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Extracellular Matrix	Extracellular Space Endoplasmic Reticulum Golgi Apparatus Perinuclear Region Of Cytoplasm
	Molecular Function	Metalloendopeptidase Activity Integrin Binding Metallopeptidase Activity Zinc Ion Binding	Hormone Activity Enzyme Binding Heme Binding Protein Homodimerization Activity
	Biological Process	Proteolysis Integrin-mediated Signaling Pathway	Cellular Calcium Ion Homeostasis Response To Oxidative Stress Embryo Implantation Negative Regulation Of Gene Expression Endoplasmic Reticulum Unfolded Protein Response Response To Vitamin D Negative Regulation Of Multicellular Organism Growth Response To Peptide Hormone Decidualization Regulation Of Hormone Biosynthetic Process Cellular Response To Hypoxia Regulation Of Store-operated Calcium Entry
Pathways
Drugs
Diseases
GWAS			Prostate cancer ( 23535732)
Protein-Protein Interactions		1 interactors: STC2	11 interactors: ADAM11 AIFM1 ARHGEF40 ARRB2 CARHSP1 EIF2B3 PEBP1 POLR2C POLR3F PPP1R8 PTN
Entrez ID		4185	8614
HPRD ID		01114	04717
Ensembl ID		ENSG00000073670	ENSG00000113739
Uniprot IDs		B4DKD2 O75078	O76061 Q6FHC9
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Store-operated Calcium Entry Negative Regulation Of Multicellular Organism Growth Regulation Of Hormone Biosynthetic Process Response To Vitamin D Decidualization Regulation Of Hormone Metabolic Process Maternal Placenta Development Embryo Implantation Maternal Process Involved In Female Pregnancy Negative Regulation Of Developmental Growth Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Hypoxia Cellular Response To Unfolded Protein Regulation Of Multicellular Organism Growth Cellular Response To Decreased Oxygen Levels ER-nucleus Signaling Pathway Response To Vitamin Cellular Response To Oxygen Levels Cellular Response To Topologically Incorrect Protein Response To Unfolded Protein Response To Endoplasmic Reticulum Stress Regulation Of Calcium Ion Transport Placenta Development Response To Nutrient Female Pregnancy Negative Regulation Of Growth Regulation Of Developmental Growth Response To Hypoxia Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Cellular Metal Ion Homeostasis Response To Oxidative Stress Response To Nutrient Levels Cellular Cation Homeostasis Cellular Ion Homeostasis Response To Peptide Hormone Response To Extracellular Stimulus Metal Ion Homeostasis Response To Peptide Reproductive Structure Development Reproductive System Development Cellular Chemical Homeostasis Ion Homeostasis Regulation Of Growth Regulation Of Ion Transport	Regulation Of Catalytic Activity Regulation Of Metabolic Process Negative Regulation Of Catalytic Activity Regulation Of Cellular Process Regulation Of Endopeptidase Activity DNA-templated Transcription, Elongation Regulation Of Peptidase Activity Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Follicle-stimulating Hormone Signaling Pathway Negative Regulation Of Smooth Muscle Cell Apoptotic Process Negative Regulation Of Translational Initiation In Response To Stress
Tagcloud ?			alleviate altering alternating american capillaries ccl2 closer coat concave convex dawley diepoxide endometrium eosin follicles ginseng glands hematoxylin nell1 ovarian pappa pla2g4a pof premature sprague uterine vcd vinylcyclohexene visible
Tagcloud (Difference) ?			alleviate altering alternating american capillaries ccl2 closer coat concave convex dawley diepoxide endometrium eosin follicles ginseng glands hematoxylin nell1 ovarian pappa pla2g4a pof premature sprague uterine vcd vinylcyclohexene visible
Tagcloud (Intersection) ?