FOXI1 and RAMAC

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FOXI1	RAMAC
Description		forkhead box I1	RNA guanine-7 methyltransferase activating subunit
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleolus	Nucleus MRNA Capping Enzyme Complex MRNA Cap Methyltransferase RNMT:RAMAC Complex
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding DNA Binding, Bending Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	RNA Binding Protein Binding Enzyme Activator Activity Molecular Function Activator Activity
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Embryo Development Ending In Birth Or Egg Hatching Cell Differentiation Inner Ear Morphogenesis Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II	7-methylguanosine MRNA Capping MRNA Processing RNA 5'-cap (guanine-N7)-methylation
Pathways
Drugs
Diseases		Thyroid dyshormonogenesis; Dyshormogenetic goiter
GWAS		Acne (severe) ( 24927181) Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs) ( 23648065)
Interacting Genes		27 interacting genes: ANKRD10 APP ARSA ATP23 BATF2 CSTF2T DTX2 FAM168B FAM83A HGS HSF4 JMJD7 KRTAP19-1 KRTAP19-7 MAGED1 MLLT10 NFKBID PIN1 RAMAC TEKT5 TENT5B UFSP1 USP54 VPS37C WDR25 WWOX YAP1	47 interacting genes: AKAP8L BAG4 BPIFA1 C10orf55 CYSRT1 DAB1 DAZAP2 DMRTB1 FAM168B FOXI1 GOLGA2 HNRNPH1 HNRNPK INCA1 KRT15 KRT31 KRT33B KRTAP1-3 KRTAP8-1 LZTS2 MAGED1 MAPK1IP1L NAF1 OXER1 PEA15 PLSCR1 PLSCR4 POU2AF1 PRR3 PSMA3 RBMX RBMY1F RBPMS RHOXF2 RINT1 SF3B4 SNRPC TEKT3 TEKT4 TNS2 TRIM23 TRIM27 TRIM42 UBC USP54 VPS37C WWOX
Entrez ID		2299	83640
HPRD ID		03057	12845
Ensembl ID		ENSG00000168269	ENSG00000169612
Uniprot IDs		E0XEN6 Q12951	Q9BTL3
PDB IDs			5E8J
Enriched GO Terms of Interacting Partners?			Identical Protein Binding Protein Binding Spliceosomal Complex Structural Constituent Of Skin Epidermis RNA Splicing Intermediate Filament Regulation Of RNA Splicing Nucleic Acid Binding Keratin Filament Transcription Coactivator Activity MRNA Splicing, Via Spliceosome MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome CD4 Receptor Binding RNA Splicing, Via Transesterification Reactions RNA Processing Regulation Of MRNA Processing Ribonucleoprotein Complex RNA Binding Positive Regulation Of Apoptotic Signaling Pathway
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