PTPN5 and TMEM201

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PTPN5	TMEM201
Description		protein tyrosine phosphatase non-receptor type 5	transmembrane protein 201
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Cell Junction	Spindle Pole Nucleus Nuclear Envelope Nuclear Inner Membrane Cytoplasm Cytoskeleton Membrane Spindle Pole Centrosome Nuclear Membrane Cortical Endoplasmic Reticulum
	Molecular Function	Phosphotyrosine Residue Binding Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Hydrolase Activity Protein Kinase Binding	Protein Binding Lamin Binding Actin Filament Binding
	Biological Process	Protein Dephosphorylation Signal Transduction	Angiogenesis Nuclear Envelope Organization Nuclear Migration Positive Regulation Of Endothelial Cell Migration Fibroblast Migration Nuclear Migration Along Microtubule Centrosome Localization Protein Localization To Nuclear Envelope
Pathways		Interleukin-37 signaling
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) ( 23648065) Myopia ( 27182965) Refractive error ( 32231278)
Interacting Genes		19 interacting genes: CCNQ CLEC4G CUL5 CXCL9 CYB561D2 ENTPD3 FYN MAPK1 MAPK3 MARCHF5 MOB1A PRKN SLC35B1 SNX4 TERF1 TMEM201 TMEM51 VTI1B ZBTB5	23 interacting genes: CLEC17A CPLX4 CYB5R3 DNAJC1 EMD FATE1 FRMD3 GOLM2 GPR152 KCNJ9 LHFPL5 LMNA LRRC25 MFF MINAR1 NDUFAF2 PTPN5 SLC26A6 TMEM237 TMEM35A TMX2 UBC VEZT
Entrez ID		84867	199953
HPRD ID		01472	17991
Ensembl ID		ENSG00000110786	ENSG00000188807
Uniprot IDs		B7Z2F8 P54829 Q86TL3	Q5SNT2
PDB IDs		2BIJ 2BV5 2CJZ 5OVR 5OVX 5OW1 6H8R 8SLS 8SLT 8SLU 9EEX 9EEY 9EEZ
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Component Organization Positive Regulation Of Defense Response ERBB2 Signaling Pathway Interleukin-34-mediated Signaling Pathway Regulation Of Golgi Inheritance Caveolin-mediated Endocytosis Positive Regulation Of Macrophage Proliferation Positive Regulation Of Organelle Organization Cardiac Neural Crest Cell Development Involved In Heart Development Trachea Formation Regulation Of Defense Response Negative Regulation Of Immune System Process Regulation Of Vesicle-mediated Transport Cellular Response To L-glutamate Outer Ear Morphogenesis ERBB3 Signaling Pathway ERBB2-ERBB3 Signaling Pathway Positive Regulation Of Inflammatory Response Immune Response-activating Signaling Pathway Bergmann Glial Cell Differentiation Reelin-mediated Signaling Pathway Positive Regulation Of Telomere Maintenance Regulation Of Immune Response ERBB Signaling Pathway Cytokine-mediated Signaling Pathway Immune Response-regulating Signaling Pathway Regulation Of Inflammatory Response Positive Regulation Of Mast Cell Degranulation Activation Of Immune Response Positive Regulation Of Immune System Process Negative Regulation Of Reactive Oxygen Species Biosynthetic Process Protein K27-linked Ubiquitination Regulation Of Golgi Organization MAP Kinase Activity Pseudopodium Organelle Localization Layer Formation In Cerebral Cortex Response To L-glutamate Positive Regulation Of Macroautophagy Schwann Cell Development Regulation Of Early Endosome To Late Endosome Transport Phospholipase Binding Positive Regulation Of Mitochondrial Fission Positive Regulation Of Neuroinflammatory Response Positive Regulation Of Chromosome Organization Positive Regulation Of Macrophage Chemotaxis Animal Organ Formation Protein K48-linked Ubiquitination Face Development Regulation Of Telomere Maintenance	Membrane Endoplasmic Reticulum Mitochondrial Outer Membrane
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