NAA11 and BAALC

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NAA11	BAALC
Description		N-alpha-acetyltransferase 11, NatA catalytic subunit	BAALC binder of MAP3K1 and KLF4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Cytosol Cilium NatA Complex Ciliary Basal Body	Nucleoplasm Cytoplasm Cytosol Postsynaptic Density Membrane Sarcoplasm Neuron Projection Membrane Raft Synapse
	Molecular Function	Protein-N-terminal Amino-acid Acetyltransferase Activity Protein Binding Protein-N-terminal-alanine Acetyltransferase Activity Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Protein N-terminal-serine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity	Protein Binding
	Biological Process	N-terminal Protein Amino Acid Acetylation
Pathways
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Chronotype ( 30696823) General risk tolerance (MTAG) ( 30643258) Refractive error ( 32231278) Schizophrenia ( 33169155)	Breast cancer and/or colorectal cancer ( 29698419) Late-onset Alzheimer's disease ( 27770636) Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes		15 interacting genes: ACOT12 AP2M1 BAALC CDC25A CDCA5 CREBRF EHMT2 HIF1A KIFAP3 MTARC1 NAA15 NAA16 TOM1 ZBTB14 ZNF202	13 interacting genes: AGTR1 AP1G1 ATP1B3 ATXN1 CHD1L CHEK2 CINP MAP3K1 MDFI NAA10 NAA11 OSBPL1A RNF2
Entrez ID		84779	79870
HPRD ID		19248	09422
Ensembl ID		ENSG00000156269	ENSG00000164929
Uniprot IDs		Q9BSU3	Q8WXS3
PDB IDs
Enriched GO Terms of Interacting Partners?		NatA Complex Nuclear Body Negative Regulation Of Thymocyte Apoptotic Process Regulation Of Thymocyte Apoptotic Process Acetyltransferase Activator Activity N-terminal Protein Amino Acid Acetylation Acetyltransferase Activity Negative Regulation Of T Cell Apoptotic Process Protein Acetylation Transcription Corepressor Binding Regulation Of Neuroblast Proliferation Negative Regulation Of Lymphocyte Apoptotic Process Regulation Of T Cell Apoptotic Process Regulation Of Macroautophagy Neuroblast Proliferation Histone H3K56 Methyltransferase Activity Positive Regulation Of Calcium-dependent Cell-cell Adhesion Positive Regulation Of Prolactin Signaling Pathway Negative Regulation Of Leukocyte Apoptotic Process Transcription Regulator Complex Regulation Of Lymphocyte Apoptotic Process	Protein-N-terminal-alanine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity Protein N-terminal-serine Acetyltransferase Activity NatA Complex Protein-N-terminal Amino-acid Acetyltransferase Activity N-terminal Protein Amino Acid Acetylation Protein Acetylation Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Angiotensin Type I Receptor Activity Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric
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