BAALC and ATP1B3

Number of citations of the paper that reports this interaction (PubMedID 26050649)
0

Data Source:
BioGRID (two hybrid)

		BAALC	ATP1B3
Description		BAALC binder of MAP3K1 and KLF4	ATPase Na+/K+ transporting subunit beta 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Postsynaptic Density Membrane Sarcoplasm Neuron Projection Membrane Raft Synapse	Cytoplasm Plasma Membrane Sodium:potassium-exchanging ATPase Complex Membrane Basolateral Plasma Membrane Apical Plasma Membrane Sperm Flagellum Melanosome Extracellular Exosome
	Molecular Function	Protein Binding	ATPase Activator Activity Protein Binding Protein-macromolecule Adaptor Activity ATPase Binding Transporter Activator Activity
	Biological Process		Monoatomic Ion Transport Potassium Ion Transport Sodium Ion Transport Intracellular Sodium Ion Homeostasis Intracellular Potassium Ion Homeostasis Sodium Ion Transmembrane Transport Sodium Ion Export Across Plasma Membrane Protein Stabilization Potassium Ion Transmembrane Transport Protein Localization To Plasma Membrane Membrane Repolarization Positive Regulation Of Sodium Ion Export Across Plasma Membrane Positive Regulation Of Potassium Ion Import Across Plasma Membrane Potassium Ion Import Across Plasma Membrane
Pathways			Basigin interactions Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS
Drugs			Bisacodyl Tegoprazan
Diseases
GWAS		Breast cancer and/or colorectal cancer ( 29698419) Late-onset Alzheimer's disease ( 27770636) Triglyceride levels x loop diuretics use interaction ( 31806883)	Blond vs. brown/black hair color ( 30531825) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Pulse pressure ( 27841878) Red cell distribution width ( 27863252 28957414 32888494) Subcortical volume (MOSTest) ( 32665545) Testicular germ cell tumor ( 26503584) Total hippocampal volume ( 30279459) Waist-hip ratio ( 28552196) White blood cell count ( 32888494)
Interacting Genes		13 interacting genes: AGTR1 AP1G1 ATP1B3 ATXN1 CHD1L CHEK2 CINP MAP3K1 MDFI NAA10 NAA11 OSBPL1A RNF2	14 interacting genes: BAALC BARD1 BRCA1 CTXN3 NLRP3 OGT PAXIP1 PEA15 SMAGP STOM TMEM98 TRIM14 UPF2 USP4
Entrez ID		79870	483
HPRD ID		09422	03521
Ensembl ID		ENSG00000164929	ENSG00000069849
Uniprot IDs		Q8WXS3	P54709
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein-N-terminal-alanine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity Protein N-terminal-serine Acetyltransferase Activity NatA Complex Protein-N-terminal Amino-acid Acetyltransferase Activity N-terminal Protein Amino Acid Acetylation Protein Acetylation Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Angiotensin Type I Receptor Activity Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric	Histone H2AK127 Ubiquitin Ligase Activity Histone H2AK129 Ubiquitin Ligase Activity BRCA1-BARD1 Complex BRCA1-B Complex Nuclear Ubiquitin Ligase Complex BRCA1-C Complex BRCA1-A Complex Ubiquitin-modified Histone Reader Activity Regulation Of Protein Ubiquitination Regulation Of Post-translational Protein Modification DNA Strand Resection Involved In Replication Fork Processing RNA Polymerase Binding Regulation Of Cell Cycle G2/M Phase Transition Regulation Of DNA Damage Checkpoint Protein K6-linked Ubiquitination Ubiquitin Protein Ligase Activity Response To Ionizing Radiation Negative Regulation Of Gene Expression Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Intracellular Signal Transduction Positive Regulation Of Protein Metabolic Process Homologous Recombination Post-translational Protein Modification Negative Regulation Of Macromolecule Metabolic Process Pyroptotic Inflammatory Response Regulation Of Protein Localization Negative Regulation Of MRNA 3'-end Processing Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Adenosine Receptor Binding Negative Regulation Of Translational Initiation Positive Regulation Of Translational Initiation Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Mitotic G2/M Transition Checkpoint Negative Regulation Of Metabolic Process DNA Recombination Regulation Of Protein Metabolic Process TORC1 Signaling Negative Regulation Of Protein Metabolic Process Positive Regulation Of TORC1 Signaling Circadian Regulation Of Gene Expression Protein Modification Process Protein Polyubiquitination Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Gene Expression Negative Regulation Of Cell Cycle G2/M Phase Transition Cellular Response To Ionizing Radiation Regulation Of Protein Modification Process Negative Regulation Of Protein Ubiquitination Regulation Of Macromolecule Biosynthetic Process
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