EBPL and DEPDC1B

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		EBPL	DEPDC1B
Description		EBP like	DEP domain containing 1B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Cholestenol Delta-isomerase Activity	GTPase Activator Activity
	Biological Process	Sterol Metabolic Process	Signal Transduction Cell Migration Positive Regulation Of Wnt Signaling Pathway Intracellular Signal Transduction
Pathways			RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOQ GTPase cycle RHOG GTPase cycle RHOJ GTPase cycle RHOU GTPase cycle RAC3 GTPase cycle RHOV GTPase cycle RHOF GTPase cycle RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172) Lipoprotein (a) levels ( 30108283) Refractive error ( 32231278)	Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Intelligence (MTAG) ( 29326435) Metabolite levels ( 23823483) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		3 interacting genes: DEPDC1B EBP NLGN3	6 interacting genes: CDC23 EBPL GRIP1 PTPRF RGS3 UHMK1
Entrez ID		84650	55789
HPRD ID		13258	16794
Ensembl ID		ENSG00000123179	ENSG00000035499
Uniprot IDs		A0A0A0MRV2 Q9BY08	Q8WUY9
PDB IDs
Enriched GO Terms of Interacting Partners?		Cholesterol Biosynthetic Process Via Lathosterol Cholesterol Biosynthetic Process Via Desmosterol C-8 Sterol Isomerase Activity Cholesterol-5,6-oxide Hydrolase Activity Steroid Delta-isomerase Activity Cholestenol Delta-isomerase Activity Rhythmic Synaptic Transmission Symmetric, GABA-ergic, Inhibitory Synapse Asymmetric, Glutamatergic, Excitatory Synapse Ossification Involved In Bone Maturation Inhibitory Postsynaptic Potential Positive Regulation Of Glutamate Receptor Signaling Pathway Postsynaptic Membrane Assembly Postsynaptic Membrane Organization Presynaptic Membrane Assembly Neuron To Neuron Synapse Presynaptic Membrane Organization Neurexin Family Protein Binding Regulation Of Respiratory Gaseous Exchange By Nervous System Process Regulation Of Glutamate Receptor Signaling Pathway Presynapse Assembly Regulation Of Respiratory System Process Neuron Cell-cell Adhesion Presynapse Organization Vocalization Behavior Regulation Of Respiratory Gaseous Exchange Positive Regulation Of Excitatory Postsynaptic Potential Positive Regulation Of Synaptic Transmission, Glutamatergic Excitatory Synapse Cholesterol Biosynthetic Process Synaptic Vesicle Endocytosis Sterol Biosynthetic Process Presynaptic Endocytosis Axon Extension Modulation Of Excitatory Postsynaptic Potential Social Behavior Membrane Assembly Positive Regulation Of Synapse Assembly
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