DEPDC1B and EBPL

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		DEPDC1B	EBPL
Description		DEP domain containing 1B	EBP like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	GTPase Activator Activity	Cholestenol Delta-isomerase Activity
	Biological Process	Signal Transduction Cell Migration Positive Regulation Of Wnt Signaling Pathway Intracellular Signal Transduction	Sterol Metabolic Process
Pathways		RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOQ GTPase cycle RHOG GTPase cycle RHOJ GTPase cycle RHOU GTPase cycle RAC3 GTPase cycle RHOV GTPase cycle RHOF GTPase cycle RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Intelligence (MTAG) ( 29326435) Metabolite levels ( 23823483) Subcortical volume (MOSTest) ( 32665545)	Hip circumference adjusted for BMI ( 34021172) Lipoprotein (a) levels ( 30108283) Refractive error ( 32231278)
Interacting Genes		6 interacting genes: CDC23 EBPL GRIP1 PTPRF RGS3 UHMK1	3 interacting genes: DEPDC1B EBP NLGN3
Entrez ID		55789	84650
HPRD ID		16794	13258
Ensembl ID		ENSG00000035499	ENSG00000123179
Uniprot IDs		Q8WUY9	A0A0A0MRV2 Q9BY08
PDB IDs
Enriched GO Terms of Interacting Partners?			Cholesterol Biosynthetic Process Via Lathosterol Cholesterol Biosynthetic Process Via Desmosterol C-8 Sterol Isomerase Activity Cholesterol-5,6-oxide Hydrolase Activity Steroid Delta-isomerase Activity Cholestenol Delta-isomerase Activity Rhythmic Synaptic Transmission Symmetric, GABA-ergic, Inhibitory Synapse Asymmetric, Glutamatergic, Excitatory Synapse Ossification Involved In Bone Maturation Inhibitory Postsynaptic Potential Positive Regulation Of Glutamate Receptor Signaling Pathway Postsynaptic Membrane Assembly Postsynaptic Membrane Organization Presynaptic Membrane Assembly Neuron To Neuron Synapse Presynaptic Membrane Organization Neurexin Family Protein Binding Regulation Of Respiratory Gaseous Exchange By Nervous System Process Regulation Of Glutamate Receptor Signaling Pathway Presynapse Assembly Regulation Of Respiratory System Process Neuron Cell-cell Adhesion Presynapse Organization Vocalization Behavior Regulation Of Respiratory Gaseous Exchange Positive Regulation Of Excitatory Postsynaptic Potential Positive Regulation Of Synaptic Transmission, Glutamatergic Excitatory Synapse Cholesterol Biosynthetic Process Synaptic Vesicle Endocytosis Sterol Biosynthetic Process Presynaptic Endocytosis Axon Extension Modulation Of Excitatory Postsynaptic Potential Social Behavior Membrane Assembly Positive Regulation Of Synapse Assembly
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