TUBB6 and LINC00941

Number of citations of the paper that reports this interaction (PubMedID 35977942)
48

Data Source:
BioGRID (unspecified method)

		TUBB6	LINC00941
Description		tubulin beta 6 class V	long intergenic non-protein coding RNA 941
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytoskeleton Microtubule Microtubule Cytoskeleton Intercellular Bridge Extracellular Exosome Mitotic Spindle
	Molecular Function	Nucleotide Binding GTPase Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding Metal Ion Binding	Promoter-enhancer Loop Anchoring Activity
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule-based Process	Positive Regulation Of Cell Population Proliferation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Canonical Wnt Signaling Pathway Chromatin Looping
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Gap junction assembly MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Recruitment of NuMA to mitotic centrosomes Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Post-chaperonin tubulin folding pathway Recycling pathway of L1 Recycling pathway of L1 Hedgehog 'off' state Cargo trafficking to the periciliary membrane Intraflagellar transport RHO GTPases activate IQGAPs RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint Carboxyterminal post-translational modifications of tubulin Carboxyterminal post-translational modifications of tubulin HCMV Early Events Assembly and cell surface presentation of NMDA receptors Activation of AMPK downstream of NMDARs Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins PKR-mediated signaling
Drugs		CYT997 Artenimol
Diseases
GWAS
Interacting Genes		6 interacting genes: DUX4 HTRA2 LINC00941 LINC01554 OGT SUMO2	7 interacting genes: ACTG1 ANXA2 ATP5F1A EEF1A2 SAFB SMAD3 TUBB6
Entrez ID		84617	100287314
HPRD ID		11349
Ensembl ID		ENSG00000176014	ENSG00000285517
Uniprot IDs		B3KS31 B4E386 K7EJ64 Q9BUF5
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein N-acetylglucosaminyltransferase Complex Non-canonical Inflammasome Complex Assembly Negative Regulation Of Non-canonical Inflammasome Complex Assembly Apoptotic Process Mitochondrial Membrane Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein Processing Protein O-acetylglucosaminyltransferase Activity Response To Herbicide Pentacyclic Triterpenoid Metabolic Process Negative Regulation Of Type 2 Mitophagy Promoter-enhancer Loop Anchoring Activity Negative Regulation Of G0 To G1 Transition Cell Death Programmed Cell Death Regulation Of Transcription By Glucose Mitochondrial Protein Catabolic Process Serine-type Endopeptidase Complex Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand NSL Complex Ubiquitin Ligase Inhibitor Activity CD40 Receptor Complex Negative Regulation Of Mitophagy Protein Maturation Regulation Of Transcription By RNA Polymerase II	Regulation Of Wound Healing Regulation Of Response To Wounding Regulation Of Cell-substrate Junction Organization Basal Body Patch Protein Kinase Binding Regulation Of Focal Adhesion Assembly Structural Constituent Of Cytoskeleton Regulation Of Stress Fiber Assembly Positive Regulation Of Receptor-mediated Endocytosis Involved In Cholesterol Transport Protease Binding AnxA2-p11 Complex PCSK9-AnxA2 Complex Regulation Of Protein Catabolic Process Negative Regulation Of Wound Healing Negative Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Response To Activity Adenyl Ribonucleotide Binding Positive Regulation Of Lipid Kinase Activity Positive Regulation Of Transforming Growth Factor Beta3 Production Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding Regulation Of Cell-matrix Adhesion Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Negative Regulation Of Protein Catabolic Process Negative Regulation Of Receptor Catabolic Process Positive Regulation Of Intracellular Cholesterol Transport Sterol Response Element Binding Double-stranded DNA Binding Paraxial Mesoderm Morphogenesis Positive Regulation Of Locomotion Positive Regulation Of Intracellular Transport Regulation Of Transepithelial Transport Positive Regulation Of Low-density Lipoprotein Particle Clearance Positive Regulation Of Plasma Membrane Repair Positive Regulation Of Intracellular Lipid Transport Angiostatin Binding Eukaryotic Translation Elongation Factor 1 Complex Regulation Of Lipid Kinase Activity Regulation Of Lung Blood Pressure Dense Body Myelin Sheath Adaxonal Region Mesoderm Morphogenesis Immune System Development Cell-cell Junction Organization Protein Localization To Bicellular Tight Junction Morphogenesis Of A Polarized Epithelium Midbody Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Proton-transporting Two-sector ATPase Complex
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