FAM120B and RPL30

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		FAM120B	RPL30
Gene Name		family with sequence similarity 120B	ribosomal protein L30
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Cytoplasm Cytosol Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit Extracellular Vesicular Exosome
	Molecular Function		RNA Binding Structural Constituent Of Ribosome Protein Binding Poly(A) RNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Differentiation	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways			Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Type 1 diabetes ( 21980299)
Protein-Protein Interactions		2 interactors: RPL30 TRAF2	13 interactors: APP CASP2 FAM120B G0S2 IL7R MAP2K7 MAP3K14 NEDD4L NFKB2 OAS1 RPL13A RPS11 ZFAND2A
Entrez ID		84498	6156
HPRD ID		11165	01595
Ensembl ID		ENSG00000112584	ENSG00000156482
Uniprot IDs		B4DL34 Q96EK7	P62888
PDB IDs			3J3B 3VI6
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of Protein Homodimerization Activity Cellular Response To Nitric Oxide Regulation Of Immunoglobulin Secretion Response To Nitric Oxide Positive Regulation Of T Cell Cytokine Production Protein Homotrimerization Regulation Of Protein Homodimerization Activity Cellular Response To Reactive Nitrogen Species Regulation Of T Cell Cytokine Production Activation Of NF-kappaB-inducing Kinase Activity Positive Regulation Of NIK/NF-kappaB Signaling Protein K63-linked Ubiquitination Tumor Necrosis Factor-mediated Signaling Pathway Protein Trimerization Positive Regulation Of Interleukin-2 Production NIK/NF-kappaB Signaling Regulation Of NIK/NF-kappaB Signaling Protein Autoubiquitination Programmed Necrotic Cell Death Necrotic Cell Death Positive Regulation Of Cytokine Production Involved In Immune Response I-kappaB Kinase/NF-kappaB Signaling TRIF-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Protein Binding MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Catabolic Process Positive Regulation Of JUN Kinase Activity Regulation Of Cytokine Production Involved In Immune Response Toll-like Receptor 4 Signaling Pathway Regulation Of JUN Kinase Activity Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Viral Transcription Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Activation Of Cysteine-type Endopeptidase Activity SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Cellular Response To Reactive Oxygen Species Protein Targeting To ER Cellular Response To Tumor Necrosis Factor Establishment Of Protein Localization To Endoplasmic Reticulum Zymogen Activation Positive Regulation Of T Cell Mediated Immunity Toll-like Receptor Signaling Pathway Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Binding Positive Regulation Of NF-kappaB Transcription Factor Activity	Immune Response Response To Cytokine Cellular Response To Stimulus Innate Immune Response Immune System Process Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Viral Life Cycle Response To Organic Substance Response To Abiotic Stimulus NIK/NF-kappaB Signaling Cellular Response To Organic Substance Response To Stimulus Positive Regulation Of Protein Metabolic Process Signal Transduction Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Defense Response Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Positive Regulation Of Neuron Apoptotic Process TRIF-dependent Toll-like Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Negative Regulation Of Formation Of Translation Preinitiation Complex MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Signaling MyD88-dependent Toll-like Receptor Signaling Pathway Cellular Response To Mechanical Stimulus Cell Communication Positive Regulation Of Neuron Death Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Metabolic Process Response To Stress Response To Osmotic Stress Viral Transcription Positive Regulation Of Immune System Process Follicular Dendritic Cell Differentiation Synaptic Growth At Neuromuscular Junction Interleukin-7-mediated Signaling Pathway Positive Regulation Of Caveolin-mediated Endocytosis Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Apoptotic Process
Tagcloud ?			ark avian avoid axl base c2 changing chicken confusion counterpart domains eyk fn ig moderately name oncogene pairs proto ptk renamed retrovirus ryk spleen subfamily transmembrane truncated ufo v
Tagcloud (Difference) ?			ark avian avoid axl base c2 changing chicken confusion counterpart domains eyk fn ig moderately name oncogene pairs proto ptk renamed retrovirus ryk spleen subfamily transmembrane truncated ufo v
Tagcloud (Intersection) ?