NEURL4 and DBNL

Number of citations of the paper that reports this interaction (PMID 17353931)
246

Data Source:
HPRD (in vivo, two hybrid)

		NEURL4	DBNL
Gene Name		neuralized E3 ubiquitin protein ligase 4	drebrin-like
Image
Gene Ontology Annotations	Cellular Component	Centriole	Golgi Membrane Ruffle Podosome Cytoplasm Cytosol Plasma Membrane Cell Cortex Postsynaptic Density Lamellipodium Cell Junction Dendrite Clathrin-coated Vesicle Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Actin Binding Protein Binding Protein C-terminus Binding Enzyme Activator Activity Protein Domain Specific Binding Actin Filament Binding
	Biological Process		Immune System Process Receptor-mediated Endocytosis Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Activation Of JUN Kinase Activity Synapse Assembly Rac Protein Signal Transduction Neuron Projection Morphogenesis Podosome Assembly Ruffle Assembly
Pathways			Apoptotic cleavage of cellular proteins Programmed Cell Death Apoptotic execution phase Caspase-mediated cleavage of cytoskeletal proteins
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: DBNL	12 interactors: ACD CASP3 LMNA MAP4K1 NEURL4 POT1 SH2D4A SH3BP2 SYK TERF1 TERF2IP ZAP70
Entrez ID		84461	28988
HPRD ID		13894	06588
Ensembl ID		ENSG00000215041	ENSG00000136279
Uniprot IDs		I3L2W2 Q96JN8	B4DDU5 Q9UJU6
PDB IDs		2E63	1X67
Enriched GO Terms of Interacting Partners?		Podosome Assembly Ruffle Assembly Rac Protein Signal Transduction Ruffle Organization Activation Of JUN Kinase Activity Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Synapse Assembly Positive Regulation Of JUN Kinase Activity Execution Phase Of Apoptosis Regulation Of JUN Kinase Activity JNK Cascade Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Activation Of MAPK Activity Synapse Organization Regulation Of JNK Cascade Regulation Of Stress-activated MAPK Cascade Positive Regulation Of MAP Kinase Activity Ras Protein Signal Transduction MAPK Cascade	Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Capping Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Regulation Of Telomerase Activity Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process RNA-dependent DNA Replication Beta Selection Telomere Maintenance Via Telomere Lengthening Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Replication Regulation Of Catalytic Activity Telomere Assembly Protection From Non-homologous End Joining At Telomere Regulation Of Chromosome Organization Protein Localization To Chromosome, Telomeric Region Positive Regulation Of Transferase Activity Positive Regulation Of Telomerase Activity Regulation Of Cellular Component Organization Negative Regulation Of Telomerase Activity Positive Regulation Of Alpha-beta T Cell Proliferation Cellular Response To Stress Regulation Of DNA Replication Positive Regulation Of Catalytic Activity Regulation Of Organelle Organization Regulation Of T Cell Proliferation Positive Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Biosynthetic Process Protein Localization To Organelle DNA Metabolic Process Positive Regulation Of Calcium-mediated Signaling Protein Localization To Chromosome Protein Autophosphorylation Peptidyl-tyrosine Autophosphorylation Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Signal Transduction Activation Of JUN Kinase Activity T Cell Selection Regulation Of Calcium-mediated Signaling Positive Regulation Of Alpha-beta T Cell Differentiation Homeostatic Process DNA Replication Regulation Of Protein Kinase Activity Response To Stress Regulation Of T Cell Activation Negative Regulation Of Transferase Activity
Tagcloud ?			compound drebrin embryonic ic implied indispensable initiating intravenous invasiveness leucine library maintenance mammosphere maternal melk otssp167 pancreas possibly promising proteasome psma1 substrates successfully suppress suppression throughput upregulated xenograft zipper
Tagcloud (Difference) ?			compound drebrin embryonic ic implied indispensable initiating intravenous invasiveness leucine library maintenance mammosphere maternal melk otssp167 pancreas possibly promising proteasome psma1 substrates successfully suppress suppression throughput upregulated xenograft zipper
Tagcloud (Intersection) ?