CYSTM1 and SYT16

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CYSTM1	SYT16
Description		cysteine rich transmembrane module containing 1	synaptotagmin 16
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Extracellular Exosome Tertiary Granule Membrane
	Molecular Function	Protein Binding	Protein Binding Phospholipid Binding Identical Protein Binding
	Biological Process
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Body mass index ( 26426971) Intelligence (MTAG) ( 29326435) Low density lipoprotein cholesterol levels ( 32154731) Worry too long after an embarrassing experience ( 29500382)	Adult body size ( 32376654) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Chronotype ( 30696823) Estimated glomerular filtration rate after 1 year in renal transplantation (recipient effect) ( 30920136) Hepatitis ( 25705159) Longevity (90 years and older) ( 24688116) Recurrence of mild malaria attacks ( 31667592) Self-rated health ( 20707712) Telomere length ( 24478790)
Interacting Genes		4 interacting genes: BAG3 GLP1R SLC22A1 SYT16	29 interacting genes: AGTRAP APOC1 APOC2 APOC4 C10orf67 CMTM5 CYSTM1 DERL3 FGF14 GSG1 HIGD1C LDAF1 MPC2 MTFR1 NCOA5 PHC2 PLEKHF2 RABAC1 REEP6 RER1 RHBDD2 RPRM RTN4 SDR16C5 SFT2D1 SYT14 TMEM239 TVP23B ZBTB14
Entrez ID		84418	83851
HPRD ID		15091	15461
Ensembl ID		ENSG00000120306	ENSG00000139973
Uniprot IDs		Q9H1C7	Q17RD7
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Psychosocial Stress Glucagon-like Peptide 1 Receptor Activity Glucagon Receptor Activity (R)-carnitine Transmembrane Transport Acetylcholine Transport Pyrimidine Nucleoside Transmembrane Transporter Activity Carnitine Transport (R)-carnitine Transmembrane Transporter Activity Norepinephrine Uptake Xenobiotic Transport Across Blood-brain Barrier Spermidine Transport Metanephric Proximal Tubule Development Toxin Transmembrane Transporter Activity Epinephrine Transport Norepinephrine:sodium Symporter Activity (R)-carnitine Transport Spermidine Transmembrane Transport Putrescine Transport Thiamine Transmembrane Transporter Activity Thiamine Transport Quaternary Ammonium Group Transmembrane Transporter Activity Dopamine:sodium Symporter Activity Proximal Tubule Development Spermidine Transmembrane Transporter Activity Putrescine Transmembrane Transporter Activity O-acyl-L-carnitine Transmembrane Transport Carnitine Transmembrane Transport Polyamine Transmembrane Transport Thiamine Transmembrane Transport Acetylcholine Transmembrane Transporter Activity Chaperone-mediated Autophagy Negative Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Aggrephagy Aggresome Assembly Post-translational Protein Targeting To Membrane, Translocation Serotonin Uptake Norepinephrine Transport Negative Regulation Of Establishment Of Protein Localization To Mitochondrion Prostaglandin Transmembrane Transporter Activity Monoamine Transmembrane Transporter Activity Inclusion Body Assembly Cellular Response To Glucagon Stimulus Activation Of Adenylate Cyclase Activity Establishment Of Localization In Cell Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Organic Cation Transmembrane Transporter Activity Azole Transmembrane Transport Amino-acid Betaine Transport Quaternary Ammonium Group Transport Catecholamine Uptake	High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Negative Regulation Of Very-low-density Lipoprotein Particle Clearance Chylomicron Remnant Clearance Triglyceride-rich Lipoprotein Particle Clearance Acylglycerol Homeostasis Triglyceride Homeostasis Regulation Of Phospholipid Catabolic Process Lipase Inhibitor Activity Signal Recognition Particle Binding Endoplasmic Reticulum Lipid Homeostasis Chylomicron Phospholipid Efflux Endoplasmic Reticulum Membrane Negative Regulation Of Lipoprotein Particle Clearance Negative Regulation Of Cholesterol Transport Plasma Lipoprotein Particle Clearance Lipoprotein Metabolic Process Regulation Of Phospholipid Metabolic Process Cholesterol Efflux Plasma Lipoprotein Particle Remodeling Negative Regulation Of Receptor-mediated Endocytosis Negative Regulation Of Phosphatidylcholine Catabolic Process Membrane Negative Regulation Of Vasculogenesis Positive Regulation Of ERBB3 Signaling Pathway Cell Adhesion Involved In Sprouting Angiogenesis Protein-containing Complex Remodeling Negative Regulation Of Lipid Transport Regulation Of Triglyceride Metabolic Process
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