COG8 and MYEF2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		COG8	MYEF2
Description		component of oligomeric golgi complex 8	myelin expression factor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane Golgi Transport Complex Trans-Golgi Network Membrane	Nucleus
	Molecular Function	Protein Binding	Nucleic Acid Binding DNA Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	Retrograde Transport, Vesicle Recycling Within Golgi Intra-Golgi Vesicle-mediated Transport Golgi Organization Protein Transport Glycosylation	Myotube Differentiation Neuron Differentiation
Pathways		COPI-mediated anterograde transport Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases		Congenital disorders of glycosylation (CDG) type II
GWAS		Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Logical memory (delayed recall) in normal cognition ( 29274321)	Skin pigmentation ( 28300201)
Interacting Genes		4 interacting genes: GEM HGS MTNR1B MYEF2	41 interacting genes: COG8 GOLGA2 LNX1 MIR128-2 MIR141 MIR15A MIR17 MIR19B1 MIR19B2 MIR200A MIR20A MIR20B MIR21 MIR221 MIR25 MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR363 MIR429 MIR9-1 MIR9-2 MIR93 MIRLET7A3 MIRLET7B MIRLET7D MIRLET7E MIRLET7F1 MIRLET7G MIRLET7I NFKBID OGT OIP5 PLEKHG4 TEX11 TRAF1 TRIM23 ZRANB1
Entrez ID		84342	50804
HPRD ID		07374	14794
Ensembl ID		ENSG00000213380	ENSG00000104177
Uniprot IDs		H3BQV3 Q96MW5	A0A0A0MQW0 Q9P2K5
PDB IDs
Enriched GO Terms of Interacting Partners?		Melatonin Receptor Activity Positive Regulation Of Transmission Of Nerve Impulse Positive Regulation Of Circadian Sleep/wake Cycle, Sleep Negative Regulation Of CGMP-mediated Signaling Regulation Of Neuronal Action Potential Negative Regulation Of Transmission Of Nerve Impulse Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep ESCRT-0 Complex Phagocytic Vesicle Lumen Nitric-oxide Synthase Complex Nitrite Reductase (NO-forming) Activity	MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing RISC Complex MRNA Base-pairing Post-transcriptional Repressor Activity Regulatory NcRNA-mediated Gene Silencing Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression Extracellular Vesicle MRNA 3'-UTR Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Translation Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Vascular Endothelial Growth Factor Production MRNA Destabilization RNA Destabilization Regulation Of Gene Expression Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Translation Regulation Of Angiogenesis Regulation Of Vasculature Development Negative Regulation Of Cytokine Production Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Macromolecule Metabolic Process Extracellular Space Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Negative Regulation Of Vasculature Development Regulation Of Metabolic Process Positive Regulation Of MRNA Metabolic Process Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Developmental Process Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Regulation Of Cell Migration Negative Regulation Of Endothelial Cell Migration Regulation Of Anatomical Structure Morphogenesis
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?