NAA38 and N4BP2L2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		NAA38	N4BP2L2
Description		N-alpha-acetyltransferase 38, NatC auxiliary subunit	NEDD4 binding protein 2 like 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm NatC Complex	Nucleus Transcription Repressor Complex Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding	Transcription Corepressor Activity Protein Binding Enzyme Binding
	Biological Process	Negative Regulation Of Apoptotic Process	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Blastocyst Development Positive Regulation Of Hematopoietic Stem Cell Proliferation Negative Regulation Of Hematopoietic Stem Cell Differentiation
Pathways		Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Heel bone mineral density ( 28869591 30598549) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Adult body size ( 32376654) Breast cancer ( 23535729) Coronary artery disease ( 29212778 33020668) Heel bone mineral density ( 30598549) LDL cholesterol ( 30275531) Logical memory (delayed recall) ( 29274321) Myocardial infarction ( 33532862)
Interacting Genes		3 interacting genes: N4BP2L2 PDE9A PRR20A	7 interacting genes: HOXA1 HUNK LMO2 NAA38 PPIA PPIH PPIL1
Entrez ID		84316	10443
HPRD ID		17491	15119
Ensembl ID		ENSG00000183011	ENSG00000244754
Uniprot IDs		I3L3Z2 I3L4V0 Q9BRA0	A0A6I8PRE0 A0A6I8PRM1 A0A6I8PRR0 A0A6I8PS46 B4DPY1 Q6ZV26 Q92802
PDB IDs		7MX2
Enriched GO Terms of Interacting Partners?		3',5'-cyclic-AMP Phosphodiesterase Activity CGMP Metabolic Process Cyclic Nucleotide Catabolic Process Negative Regulation Of Neural Precursor Cell Proliferation 3',5'-cyclic-GMP Phosphodiesterase Activity Positive Regulation Of Long-term Synaptic Potentiation CGMP Catabolic Process 3',5'-cyclic-nucleotide Phosphodiesterase Activity Negative Regulation Of CAMP/PKA Signal Transduction Negative Regulation Of Stem Cell Differentiation Negative Regulation Of Hematopoietic Stem Cell Differentiation Regulation Of Hematopoietic Stem Cell Proliferation Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Hematopoietic Stem Cell Proliferation Regulation Of Hematopoietic Stem Cell Differentiation Blastocyst Development Cyclic Purine Nucleotide Metabolic Process Regulation Of Long-term Synaptic Potentiation Regulation Of CAMP/PKA Signal Transduction Positive Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Stem Cell Proliferation Regulation Of Hematopoietic Progenitor Cell Differentiation	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Peptidyl-prolyl Isomerization Cyclosporin A Binding Isomerase Activity Protein Folding Positive Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Semicircular Canal Formation Regulation Of Viral Genome Replication Abducens Nerve Formation Optokinetic Behavior Negative Regulation Of Protein K48-linked Ubiquitination NatC Complex Regulation Of Viral Life Cycle Cell Adhesion Molecule Production U4/U6 SnRNP U5 SnRNA 3'-end Processing U1 SnRNA 3'-end Processing Regulation Of Viral Process MRNA Metabolic Process Outer Ear Morphogenesis Embryonic Neurocranium Morphogenesis Virion Binding Regulation Of Protein K48-linked Ubiquitination Activation Of Protein Kinase B Activity Negative Regulation Of Viral Life Cycle Endothelial Cell Activation Heparan Sulfate Binding Negative Regulation Of Protein Polyubiquitination Negative Regulation Of Stress-activated Protein Kinase Signaling Cascade Negative Regulation Of Stress-activated MAPK Cascade MRNA Splicing, Via Spliceosome Spliceosomal Complex RNA Splicing, Via Transesterification Reactions Exoribonuclease Complex Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) TRAMP-dependent TRNA Surveillance Pathway TRNA Surveillance RRNA 3'-end Processing Nucleolar Exosome (RNase Complex) U4 SnRNA 3'-end Processing Nuclear Polyadenylation-dependent RRNA Catabolic Process TRNA Decay Nuclear MRNA Surveillance Nucleus RNA Processing Cytoplasmic Exosome (RNase Complex) RNA Exonuclease Activity RRNA Catabolic Process Nuclear Exosome (RNase Complex)
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