NUDT22 and IKZF5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NUDT22	IKZF5
Description		nudix hydrolase 22	IKAROS family zinc finger 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Nucleus Protein-containing Complex
	Molecular Function	Protein Binding UDP-sugar Diphosphatase Activity Hydrolase Activity Metal Ion Binding GDP-mannose Hydrolase Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Protein Domain Specific Binding Metal Ion Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 28067908) Fruit consumption ( 32066663)
Interacting Genes		22 interacting genes: ARID5A DDIT4L DNAL4 IKZF5 INCA1 KLHL26 LHX3 RUSC1 SAXO1 TCF4 TLE5 USP54 WDR54 ZBTB33 ZMYND12 ZNF143 ZNF19 ZNF343 ZNF398 ZNF581 ZNF648 ZNF655	9 interacting genes: CCDC85B IKZF1 IKZF2 IKZF3 IKZF4 LDOC1 NUDT22 PIAS1 UBE2I
Entrez ID		84304	64376
HPRD ID		14434	05873
Ensembl ID		ENSG00000149761	ENSG00000095574
Uniprot IDs		Q9BRQ3	Q9H5V7
PDB IDs		5LF9 5LOR 5LOU 5R50 5R51 5R52 5R53 5R54 5R55 5R56 5R57 5R58 5R59 5R5A 5R5B 5R5C 5R5D 5R5E 5R5F 5R5G 5R5H 5R5I 5R5J 5R5K 5R5L 5R5M 5R5N 5R5O 5R5P 5R5Q 5R5R 5R5S 5RKZ
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription By RNA Polymerase II DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Zinc Ion Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process	Regulation Of DNA-templated Transcription Negative Regulation Of DNA-templated Transcription Presynaptic Cytosol Postsynaptic Cytosol SUMO Transferase Activity Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Protein Domain Specific Binding DNA-binding Transcription Factor Activity Negative Regulation Of RNA Metabolic Process Regulation Of RNA Metabolic Process Protein Sumoylation Mesoderm Development Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II SUMO Conjugating Enzyme Activity GDP-mannose Hydrolase Activity Nucleoplasm RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding UDP-sugar Diphosphatase Activity PML Body RING-like Zinc Finger Domain Binding Zinc Ion Binding SUMO Ligase Complex HLH Domain Binding Nucleus DNA Binding Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Small Protein Activating Enzyme Binding Maternal Process Involved In Parturition Regulation Of Primary Metabolic Process Negative Regulation Of Biosynthetic Process Metal Ion Binding Delta-catenin Binding Mitotic Nuclear Membrane Reassembly Maternal Placenta Development Cellular Response To Muramyl Dipeptide Negative Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Metabolic Process Transferase Complex SUMO Ligase Activity Positive Regulation Of Protein Sumoylation Lymphocyte Differentiation Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of Metabolic Process
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