SETD3 and MYOD1

Number of citations of the paper that reports this interaction (PMID 21832073)
2

Data Source:
BioGRID (pull down)

		SETD3	MYOD1
Gene Name		SET domain containing 3	myogenic differentiation 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Myofibril
	Molecular Function	RNA Polymerase II Activating Transcription Factor Binding Transcription Coactivator Activity Histone Methyltransferase Activity (H3-K4 Specific) Histone Methyltransferase Activity (H3-K36 Specific)	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Core Promoter Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Chromatin DNA Binding Ubiquitin Protein Ligase Binding Nuclear Hormone Receptor Binding Protein Heterodimerization Activity E-box Binding
	Biological Process	Transcription, DNA-templated Histone H3-K36 Methylation Peptidyl-lysine Trimethylation Peptidyl-lysine Monomethylation Peptidyl-lysine Dimethylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Muscle Cell Differentiation Histone H3-K4 Methylation	Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Protein Phosphorylation Muscle Organ Development Myoblast Fate Determination Skeletal Muscle Tissue Development Cellular Response To Starvation Myotube Cell Development Myotube Differentiation Involved In Skeletal Muscle Regeneration Skeletal Muscle Cell Differentiation Muscle Cell Differentiation Muscle Cell Fate Commitment Positive Regulation Of Skeletal Muscle Tissue Regeneration Regulation Of RNA Splicing Skeletal Muscle Fiber Adaptation Histone H3 Acetylation Histone H4 Acetylation Positive Regulation Of Myoblast Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Skeletal Muscle Fiber Development Positive Regulation Of Skeletal Muscle Fiber Development Positive Regulation Of Muscle Cell Differentiation Cellular Response To Glucocorticoid Stimulus Cellular Response To Estradiol Stimulus Cellular Response To Oxygen Levels Positive Regulation Of Myoblast Fusion
Pathways			CDO in myogenesis Myogenesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: APP MYOD1 SRPK1	61 interactors: ASCL3 BHLHA15 BHLHE40 BHLHE41 C2orf88 CALM1 CALM2 CALM3 CARM1 CDC34 CDK2 CDK4 CDKN1C CIB2 CREBBP CSRP3 ELSPBP1 EP300 HAND1 HDAC1 HEY1 HIST1H3A HSP90AA1 ID1 ID2 ID3 ID4 IFRD1 JUN KAT2B KAT5 KPNA3 MDFI MEF2A MEF2C MOS MYOCD NCOR1 NCOR2 NR2F2 PHB2 POLR2G PRKCA PRMT5 PSMD4 PSME2 RB1 RORA RUNX1 RXRA SETD3 SMAD3 SMAD4 SMAD7 SP1 SRF STAT3 SUV39H1 TCF3 TCF4 TWIST1
Entrez ID		84193	4654
HPRD ID		08664	01166
Ensembl ID		ENSG00000183576	ENSG00000129152
Uniprot IDs		Q86TU7	P15172
PDB IDs		3SMT
Enriched GO Terms of Interacting Partners?		Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of RNA Splicing Protein Phosphorylation Myoblast Fate Determination Myotube Differentiation Involved In Skeletal Muscle Regeneration Skeletal Muscle Fiber Adaptation Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Developmental Growth Regulation Of Developmental Growth Cell Development Phosphorylation Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Skeletal Muscle Tissue Regeneration Axon Choice Point Recognition Positive Regulation Of Skeletal Muscle Fiber Development Myoblast Fate Commitment MRNA Processing Neuron Remodeling Sperm Chromatin Condensation Skeletal Muscle Adaptation Growth MRNA Metabolic Process RNA Processing Phosphate-containing Compound Metabolic Process Wound Healing Regulation Of Growth Muscle Cell Fate Commitment Positive Regulation Of Myoblast Differentiation Positive Regulation Of Myoblast Fusion Cellular Copper Ion Homeostasis Cellular Response To Estradiol Stimulus Regulation Of Skeletal Muscle Fiber Development RNA Metabolic Process Response To Wounding Cellular Protein Modification Process Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Positive Regulation Of Viral Genome Replication Regulation Of Myoblast Fusion Chromatin Organization Copper Ion Homeostasis Suckling Behavior Skeletal Muscle Fiber Development Cell Differentiation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Response To Stress Gene Expression	Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Transcription, DNA-templated Negative Regulation Of Gene Expression RNA Biosynthetic Process Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Metabolic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of Metabolic Process RNA Metabolic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Rhythmic Process Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nucleic Acid-templated Transcription Organ Development Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Anatomical Structure Morphogenesis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Organic Substance Organ Morphogenesis Anatomical Structure Development Cardiovascular System Development Regulation Of Cell Differentiation Heart Development Response To Growth Factor Biosynthetic Process Regulation Of Cell Cycle Developmental Process Cell Differentiation System Development Regulation Of Binding
Tagcloud ?			antitrypsin chn chondrosarcoma desmin desmoplastic ectomesenchymoma etv1 ews extraskeletal fkhr fli1 hhf35 liposarcoma mic2 myxoid p22 pax pnet q12 q14 q22 q24 q35 ssx1 stt stts syt tec witnessed
Tagcloud (Difference) ?			antitrypsin chn chondrosarcoma desmin desmoplastic ectomesenchymoma etv1 ews extraskeletal fkhr fli1 hhf35 liposarcoma mic2 myxoid p22 pax pnet q12 q14 q22 q24 q35 ssx1 stt stts syt tec witnessed
Tagcloud (Intersection) ?