GTF2IRD2 and CDK20

Number of citations of the paper that reports this interaction (PubMedID 18508765)
36

Data Source:
BioGRID (two hybrid)

		GTF2IRD2	CDK20
Description		GTF2I repeat domain containing 2	cyclin dependent kinase 20
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cilium Cell Projection
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Neural Tube Closure Regulation Of Smoothened Signaling Pathway Floor Plate Formation Embryonic Camera-type Eye Development Negative Regulation Of Smoothened Signaling Pathway Embryonic Skeletal System Development Cell Division Regulation Of Cell Cycle Roof Of Mouth Development Protein Localization To Cilium Regulation Of Protein Maturation Embryonic Brain Development
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Atrial fibrillation ( 30061737) Red cell distribution width ( 27863252 28957414 32888494)
Interacting Genes		3 interacting genes: CDK20 FBXO25 TRIM54	9 interacting genes: CCNH CDK2 CILK1 CSNK2B GTF2IRD1 GTF2IRD2 PANK4 PPP5C TRIM2
Entrez ID		84163	23552
HPRD ID		16402	13010
Ensembl ID		ENSG00000196275	ENSG00000156345
Uniprot IDs		A0A494C0I1 Q86UP8	A0A0S2Z562 A0A0S2Z5B6 Q8IZL9
PDB IDs
Enriched GO Terms of Interacting Partners?			Phosphate-containing Compound Metabolic Process Phosphorylation Protein Phosphorylation DNA-templated Transcription Nucleobase-containing Compound Biosynthetic Process Protein Modification Process Kinase Activity Cyclin-dependent Protein Kinase Holoenzyme Complex Male Germ Cell Nucleus ATP Binding Brain-derived Neurotrophic Factor Receptor Activity Transition Between Slow And Fast Fiber Macromolecule Metabolic Process Y Chromosome Positive Regulation Of Heterochromatin Formation Cyclin A1-CDK2 Complex Cyclin E2-CDK2 Complex Positive Regulation Of DNA-templated DNA Replication Initiation Positive Regulation Of Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Phosphatase Activity Pantothenate Kinase Activity Transcription Factor TFIIK Complex Positive Regulation Of Chromatin Organization Protein Serine/threonine Kinase Activity Cyclin-dependent Protein Kinase Activity Cyclin A2-CDK2 Complex Cyclin E1-CDK2 Complex Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Trans-synaptic Signaling By BDNF, Modulating Synaptic Transmission Brain-derived Neurotrophic Factor Binding Response To Arachidonate Peptidyl-serine Dephosphorylation CAK-ERCC2 Complex X Chromosome Brain-derived Neurotrophic Factor Receptor Signaling Pathway Neurotrophin Receptor Activity Trans-synaptic Signaling By BDNF Neurotrophin Binding Protein Kinase Activity Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Metabolic Process Release From Viral Latency Pantothenate Metabolic Process Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Histone Kinase Activity Positive Regulation Of Activin Receptor Signaling Pathway Negative Regulation Of Viral Life Cycle Regulation Of G1/S Transition Of Mitotic Cell Cycle Protection From Non-homologous End Joining At Telomere
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