DTNBP1 and CSGALNACT1

		DTNBP1	CSGALNACT1
Description		dystrobrevin binding protein 1	chondroitin sulfate N-acetylgalactosaminyltransferase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Endosome Membrane Postsynaptic Density Microtubule Cytoskeleton Membrane Sarcoplasm Axon Growth Cone Midbody Cytoplasmic Vesicle Membrane Synaptic Vesicle Membrane BLOC-1 Complex Cytoplasmic Vesicle Asymmetric Synapse Melanosome Membrane Sarcolemma Neuron Projection Neuronal Cell Body Dendritic Spine Synapse Postsynaptic Membrane Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Glutamatergic Synapse Axon Cytoplasm	Golgi Membrane Golgi Apparatus Membrane Golgi Cisterna Membrane
	Molecular Function	Protein Binding	Protein Binding Acetylgalactosaminyltransferase Activity Peptidoglycan Glycosyltransferase Activity Glucuronosyltransferase Activity Transferase Activity Metal Ion Binding Glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase Activity Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase Activity
	Biological Process	Kidney Development Positive Regulation Of Neurotransmitter Secretion Positive Regulation Of Receptor Internalization Blood Coagulation Memory Anterograde Axonal Transport Regulation Of Signal Transduction Positive Regulation Of Gene Expression Regulation Of Dopamine Secretion Actin Cytoskeleton Organization Neuron Projection Development Melanosome Organization Anterograde Synaptic Vesicle Transport Neuron Projection Morphogenesis Dendrite Morphogenesis Retina Development In Camera-type Eye Platelet Dense Granule Organization Regulation Of Dopamine Receptor Signaling Pathway Cilium Assembly Negative Regulation Of Dendritic Spine Morphogenesis Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization Protein Transmembrane Transport Regulation Of Synaptic Vesicle Exocytosis	Endochondral Ossification Heparan Sulfate Proteoglycan Biosynthetic Process UDP-N-acetylgalactosamine Metabolic Process Proteoglycan Biosynthetic Process Extracellular Matrix Organization Heparin Proteoglycan Biosynthetic Process UDP-glucuronate Metabolic Process Chondroitin Sulfate Proteoglycan Biosynthetic Process Dermatan Sulfate Proteoglycan Biosynthetic Process Chondroitin Sulfate Proteoglycan Metabolic Process Cartilage Development
Pathways		Golgi Associated Vesicle Biogenesis	CS-GAG biosynthesis
Drugs
Diseases		Hermansky-Pudlak syndrome (HPS)
GWAS		Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Corneal astigmatism ( 30306274) Femur bone mineral density x serum urate levels interaction ( 34046847) Liver enzyme levels (alkaline phosphatase) ( 33972514) Multiple myeloma ( 27363682) Serum alkaline phosphatase levels ( 33547301) Squamous cell carcinoma ( 31174203)	Appendicular lean mass ( 33097823) Glucocorticoid-induced osteonecrosis (age 10 years and older) ( 26265699) Height ( 31562340) Language performance in older adults (adjusted for episodic memory) ( 28577822) Low density lipoprotein cholesterol levels ( 32154731) Lung function in never smokers (low FEV1 vs average FEV1) ( 26423011) Oropharynx cancer ( 27749845) Persistent hepatitis B virus infection ( 27244555) Response to antidepressant treatment (citalopram) ( 23726668) Response to antidepressants (symptom improvement) ( 29160301) Triglyceride levels ( 32154731) Venous thromboembolism ( 33592630)
Interacting Genes		51 interacting genes: ABI3 AKAP6 ARFIP2 BICRAL BLOC1S5 BLOC1S6 BRF1 CCDC146 CCNA2 CCND3 CMYA5 DCTN1 DGCR6L DRC12 DST DTNA DTNB ELOVL7 HAUS1 IFT20 IPO5 KALRN KANSL1 KIAA0408 KIFC3 KRT75 MACF1 NBEA NDN NECAB2 NUF2 OIP5 P4HA3 PSME3 RAB11A RBSN SDCBP SFR1 SHFL SNAPIN SRGAP3 SSC5D SYNE1 TNKS TRAF3IP1 TRIM2 TRIM27 TRIM9 VRK2 WASHC3 ZNF490	1 interacting genes: SPAG4
Entrez ID		84062	55790
HPRD ID		06190	13114
Ensembl ID		ENSG00000047579	ENSG00000147408
Uniprot IDs		A0A087WYP9 A0A0S2Z5U8 A6NFV8 D6RJC6 Q96EV8	Q8TDX6
PDB IDs
Enriched GO Terms of Interacting Partners?		Establishment Of Melanosome Localization Melanosome Localization Melanosome Transport Pigment Granule Transport Pigment Granule Localization Axonal Transport Microtubule-based Movement Transport Along Microtubule BLOC-1 Complex Anterograde Synaptic Vesicle Transport Axo-dendritic Transport Cytoskeleton-dependent Intracellular Transport Microtubule-based Process Microtubule-based Transport Establishment Of Vesicle Localization Axon Cytoplasm Microvesicle Vesicle Localization Endosome To Melanosome Transport Plasma Membrane Bounded Cell Projection Organization Synaptic Vesicle Transport Intracellular Transport Melanosome Organization Cellular Localization Nuclear Envelope Pigment Granule Organization Cell Projection Organization Anterograde Axonal Transport Organelle Organization Vesicle Transport Along Microtubule Cytoskeleton Organization Cytoplasm Microtubule Binding Nuclear Membrane Vesicle Cytoskeletal Trafficking Centrosome Establishment Of Protein Localization Cytoskeleton Secretion Of Lysosomal Enzymes Protein Transmembrane Transport Regulation Of Organelle Organization Establishment Of Localization In Cell Positive Regulation Of Pigment Cell Differentiation Spindle Pole Plasma Membrane Bounded Cell Projection Assembly Neuron Projection Development Organelle Transport Along Microtubule Regulation Of Actin Nucleation Cell Projection Assembly Protein Transport	Meiotic Nuclear Membrane Microtubule Tethering Complex Positive Regulation Of Neurotransmitter Secretion Anterograde Synaptic Vesicle Transport Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization Platelet Dense Granule Organization Melanosome Membrane Regulation Of Dopamine Secretion Regulation Of Dopamine Receptor Signaling Pathway Asymmetric Synapse Regulation Of Glutamate Secretion Negative Regulation Of Dendritic Spine Morphogenesis Regulation Of Glutamate Secretion, Neurotransmission Positive Regulation Of Glutamate Secretion Sarcoplasm Positive Regulation Of Amino Acid Transport Positive Regulation Of Glutamate Secretion, Neurotransmission BLOC-1 Complex Negative Regulation Of Dendritic Spine Development Positive Regulation Of Receptor Internalization Protein-membrane Adaptor Activity Regulation Of Catecholamine Secretion Vesicle Transport Along Microtubule Synaptic Vesicle Transport Positive Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Dendritic Spine Morphogenesis Hippocampal Mossy Fiber To CA3 Synapse Anterograde Axonal Transport Melanosome Organization Pigment Granule Organization Nuclear Inner Membrane Dendrite Morphogenesis Regulation Of Synaptic Vesicle Exocytosis Positive Regulation Of Receptor-mediated Endocytosis Regulation Of Dendritic Spine Development Vesicle Cytoskeletal Trafficking Axon Cytoplasm Axonal Transport Secretory Granule Organization Protein Transmembrane Transport Regulation Of Receptor Internalization Retina Development In Camera-type Eye Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Amine Transport Axo-dendritic Transport Regulation Of Neurotransmitter Secretion Organelle Transport Along Microtubule Schaffer Collateral - CA1 Synapse Coagulation Blood Coagulation Establishment Of Vesicle Localization
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