CSGALNACT1

Description		chondroitin sulfate N-acetylgalactosaminyltransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane Golgi Cisterna Membrane
	Molecular Function	Protein Binding Acetylgalactosaminyltransferase Activity Peptidoglycan Glycosyltransferase Activity Glucuronosyltransferase Activity Transferase Activity Metal Ion Binding Glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase Activity Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase Activity
	Biological Process	Endochondral Ossification Heparan Sulfate Proteoglycan Biosynthetic Process UDP-N-acetylgalactosamine Metabolic Process Proteoglycan Biosynthetic Process Extracellular Matrix Organization Heparin Proteoglycan Biosynthetic Process UDP-glucuronate Metabolic Process Chondroitin Sulfate Proteoglycan Biosynthetic Process Dermatan Sulfate Proteoglycan Biosynthetic Process Chondroitin Sulfate Proteoglycan Metabolic Process Cartilage Development
Pathways		CS-GAG biosynthesis
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Glucocorticoid-induced osteonecrosis (age 10 years and older) ( 26265699) Height ( 31562340) Language performance in older adults (adjusted for episodic memory) ( 28577822) Low density lipoprotein cholesterol levels ( 32154731) Lung function in never smokers (low FEV1 vs average FEV1) ( 26423011) Oropharynx cancer ( 27749845) Persistent hepatitis B virus infection ( 27244555) Response to antidepressant treatment (citalopram) ( 23726668) Response to antidepressants (symptom improvement) ( 29160301) Triglyceride levels ( 32154731) Venous thromboembolism ( 33592630)
Novel Interacting Genes		1 novel interacting genes: DTNBP1
Interacting Genes		1 interacting genes: SPAG4
Entrez ID		55790
HPRD ID		13114
Ensembl ID		ENSG00000147408
Uniprot IDs		Q8TDX6
PDB IDs
Enriched GO Terms of Interacting Partners?		Meiotic Nuclear Membrane Microtubule Tethering Complex Positive Regulation Of Neurotransmitter Secretion Anterograde Synaptic Vesicle Transport Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization Platelet Dense Granule Organization Melanosome Membrane Regulation Of Dopamine Secretion Regulation Of Dopamine Receptor Signaling Pathway Asymmetric Synapse Regulation Of Glutamate Secretion Negative Regulation Of Dendritic Spine Morphogenesis Regulation Of Glutamate Secretion, Neurotransmission Positive Regulation Of Glutamate Secretion Sarcoplasm Positive Regulation Of Amino Acid Transport Positive Regulation Of Glutamate Secretion, Neurotransmission BLOC-1 Complex Negative Regulation Of Dendritic Spine Development Positive Regulation Of Receptor Internalization Protein-membrane Adaptor Activity Regulation Of Catecholamine Secretion Vesicle Transport Along Microtubule Synaptic Vesicle Transport Positive Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Dendritic Spine Morphogenesis Hippocampal Mossy Fiber To CA3 Synapse Anterograde Axonal Transport Melanosome Organization Pigment Granule Organization Nuclear Inner Membrane Dendrite Morphogenesis Regulation Of Synaptic Vesicle Exocytosis Positive Regulation Of Receptor-mediated Endocytosis Regulation Of Dendritic Spine Development Vesicle Cytoskeletal Trafficking Axon Cytoplasm Axonal Transport Secretory Granule Organization Protein Transmembrane Transport Regulation Of Receptor Internalization Retina Development In Camera-type Eye Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Amine Transport Axo-dendritic Transport Regulation Of Neurotransmitter Secretion Organelle Transport Along Microtubule Schaffer Collateral - CA1 Synapse Coagulation Blood Coagulation Establishment Of Vesicle Localization
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