STK40 and SLIRP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		STK40	SLIRP
Description		serine/threonine kinase 40	SRA stem-loop interacting RNA binding protein
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Acrosomal Vesicle Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Sperm Flagellum Perinuclear Region Of Cytoplasm Ribonucleoprotein Complex
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	Respiratory System Process Glycogen Metabolic Process Regulation Of Gene Expression Lung Development Multicellular Organism Growth Negative Regulation Of Apoptotic Process Regulation Of MAPK Cascade Lung Alveolus Development Lung Morphogenesis	Negative Regulation Of Mitochondrial RNA Catabolic Process Mitochondrion Organization Spermatid Development Single Fertilization Flagellated Sperm Motility Mitochondrial MRNA Polyadenylation Negative Regulation Of Mitochondrial MRNA Catabolic Process
Pathways			Mitochondrial RNA degradation Mitochondrial mRNA modification
Drugs
Diseases
GWAS		Neutrophil count ( 32888494)
Interacting Genes		6 interacting genes: APP COPS6 LRRK2 NEDD4L POLA2 SLIRP	16 interacting genes: AMOT CCDC102B CSNK2A1 DMRTB1 EXOSC8 GOLGA6L9 KRT27 KRT31 KRT40 MTUS2 NDUFAB1 PICK1 PNMA1 RBPMS STK40 WTAP
Entrez ID		83931	81892
HPRD ID		11359	12639
Ensembl ID		ENSG00000196182	ENSG00000119705
Uniprot IDs		Q8N2I9	A0A087WUN7 Q9GZT3
PDB IDs		5L2Q	8ANY
Enriched GO Terms of Interacting Partners?		Golgi-associated Vesicle Positive Regulation Of Endocytosis Cellular Response To Catecholamine Stimulus Cellular Response To Manganese Ion Response To Catecholamine Response To Manganese Ion Positive Regulation Of Protein Catabolic Process Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Neuromuscular Junction Development Synapse Organization Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of CAMP/PKA Signal Transduction Macromolecule Metabolic Process Regulation Of Synapse Organization Modulation Of Excitatory Postsynaptic Potential Regulation Of Membrane Depolarization Regulation Of Endocytosis Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Protein Catabolic Process Cellular Response To Curcumin Caveola Neck GTP-dependent Protein Kinase Activity Wnt Signalosome Assembly Acetylcholine Receptor Activator Activity Positive Regulation Of Tumor Necrosis Factor Production Regulation Of Membrane Potential Regulation Of Response To Endoplasmic Reticulum Stress Endocytosis Regulation Of Calcium-mediated Signaling Lipoprotein Particle Cell Junction Organization Positive Regulation Of Protein Import Negative Regulation Of Mitochondrial MRNA Catabolic Process Negative Regulation Of Mitochondrial RNA Catabolic Process Negative Regulation Of Late Endosome To Lysosome Transport Amphisome Peroxidase Inhibitor Activity Negative Regulation Of Protein Processing Involved In Protein Targeting To Mitochondrion Beta-catenin Destruction Complex Binding Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Catabolic Process Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production	Structural Constituent Of Skin Epidermis Structural Molecule Activity Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Cytoskeleton Intermediate Filament
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