TAF10 and TAF12

Number of citations of the paper that reports this interaction (PMID 7729427)
41

Data Source:
HPRD (in vivo, in vitro)

		TAF10	TAF12
Gene Name		TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
Image
Gene Ontology Annotations	Cellular Component	PCAF Complex Nucleus Nucleoplasm Transcription Factor TFIID Complex Cytoplasm STAGA Complex Transcription Factor TFTC Complex Perinuclear Region Of Cytoplasm	PCAF Complex Nucleoplasm Transcription Factor TFIID Complex STAGA Complex Transcription Factor TFTC Complex
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Enzyme Binding Estrogen Receptor Binding RNA Polymerase Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Transcription Factor Binding Protein Heterodimerization Activity
	Biological Process	Chromatin Organization DNA-templated Transcription, Initiation Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Histone Deubiquitination Histone H3 Acetylation Protein Homooligomerization	Chromatin Organization DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Histone H3 Acetylation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Nucleic Acid-templated Transcription
Pathways		RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Chromatin organization HIV Infection HATs acetylate histones RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation Chromatin modifying enzymes RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome	RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Chromatin organization HIV Infection HATs acetylate histones RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation Chromatin modifying enzymes RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome
Drugs
Diseases
GWAS
Protein-Protein Interactions		23 interactors: ATXN7 ESR1 FANCA FTL HIST3H3 POLR2A PSMC5 SETD7 SUPT7L TAF1 TAF11 TAF12 TAF13 TAF2 TAF3 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 TBP UBE2I	22 interactors: ATF7 CPSF1 HIST3H3 NFYA NFYB NFYC PRKAR2B TAF1 TAF10 TAF11 TAF15 TAF1A TAF2 TAF4 TAF4B TAF5 TAF6 TAF7 TAF8 TAF9 TBP UBE2I
Entrez ID		6881	6883
HPRD ID		15972	15981
Ensembl ID			ENSG00000120656
Uniprot IDs		Q12962	Q16514
PDB IDs		3M53 3M54 3M55 3M56 3M57 3M58 3M59 3M5A	1H3O
Enriched GO Terms of Interacting Partners?		Transcription Elongation From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation DNA-templated Transcription, Initiation Viral Process Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Peptidyl-lysine Modification Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Chromatin Modification Regulation Of Metabolic Process Histone Modification Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Cellular Metabolic Process Internal Protein Amino Acid Acetylation Positive Regulation Of Transcription, DNA-templated Protein Acetylation Chromatin Organization Chromosome Organization Maintenance Of Protein Location In Nucleus Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Histone H3 Acetylation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Peptidyl-amino Acid Modification Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Process Organelle Organization Metabolic Process	DNA-templated Transcription, Elongation Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription Initiation From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Viral Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Cellular Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Peptidyl-lysine Modification Protein Acetylation Positive Regulation Of Metabolic Process Metabolic Process Histone H3 Acetylation Histone Modification DNA-templated Transcription, Termination Regulation Of Cellular Process Chromatin Silencing At RDNA Regulation Of Transcription From RNA Polymerase II Promoter Peptidyl-amino Acid Modification Chromatin Modification Chromosome Organization Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter
Tagcloud ?		aam adenosyl adomet alkyl amine analogues atom attached azaalkyl bonding coenzyme complexed daam der hexyl hexylaminoethyl methionine methylates nonhistone oestrogen replaces set7 stabilizes stabilizing symmetry unexpectedly van waals weaker	adjacent characterised directed directing elements embryonic hepatocyte heterodimer highlighting hnf4a inactivation instructive interacts maintain maturation mutually natal occupancy pausing pic post promotes proximal start subset taf4 tafs tfiid
Tagcloud (Difference) ?		aam adenosyl adomet alkyl amine analogues atom attached azaalkyl bonding coenzyme complexed daam der hexyl hexylaminoethyl methionine methylates nonhistone oestrogen replaces set7 stabilizes stabilizing symmetry unexpectedly van waals weaker	adjacent characterised directed directing elements embryonic hepatocyte heterodimer highlighting hnf4a inactivation instructive interacts maintain maturation mutually natal occupancy pausing pic post promotes proximal start subset taf4 tafs tfiid
Tagcloud (Intersection) ?