INHBE and SDR9C7

		INHBE	SDR9C7
Description		inhibin subunit beta E	short chain dehydrogenase/reductase family 9C member 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Matrix	Cytoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	Cytokine Activity Hormone Activity Growth Factor Activity	All-trans-retinol Dehydrogenase (NAD+) Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
	Biological Process	Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Activin Receptor Signaling Pathway Negative Regulation Of Adipose Tissue Development	Steroid Metabolic Process Retinol Metabolic Process
Pathways		Glycoprotein hormones	The canonical retinoid cycle in rods (twilight vision)
Drugs
Diseases
GWAS		HDL cholesterol ( 30275531) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Platelet count ( 27863252 32888494) Plateletcrit ( 32888494) Red cell distribution width ( 32888494) Urate levels ( 23263486)	Alzheimer's disease (survival time) ( 25649651) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Cerebral amyloid deposition (PET imaging) ( 30361487) Depressive symptoms (binary sum-score) ( 31530331) Familial lung cancer ( 29924316) Headache ( 29397368) Migraine ( 27322543) Migraine without aura ( 27322543) Refractive error ( 32231278)
Interacting Genes		1 interacting genes: FST	1 interacting genes: CFTR
Entrez ID		83729	121214
HPRD ID		11047	15235
Ensembl ID		ENSG00000139269	ENSG00000170426
Uniprot IDs		P58166	Q8NEX9
PDB IDs
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Enamel Mineralization Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Negative Regulation Of Adipose Tissue Development Amelogenesis ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Golgi-associated Vesicle Membrane Cellular Response To Forskolin Response To Forskolin Chloride Transmembrane Transporter Activity Sperm Capacitation Regulation Of Adipose Tissue Development Bicarbonate Transport Water Transport Multicellular Organismal-level Water Homeostasis Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Ion Transmembrane Transporter Activity Cholesterol Biosynthetic Process 14-3-3 Protein Binding Fluid Transport Transepithelial Transport Activin Receptor Signaling Pathway Vesicle Docking Involved In Exocytosis Positive Regulation Of Transporter Activity ABC-type Transporter Activity Sterol Biosynthetic Process Chloride Channel Complex Positive Regulation Of Biomineral Tissue Development Cellular Response To CAMP Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Vesicle Docking Cholesterol Transport Clathrin-coated Endocytic Vesicle Membrane Odontogenesis Of Dentin-containing Tooth Chloride Channel Activity Multicellular Organismal-level Chemical Homeostasis Regulation Of Cellular PH
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